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Excited to share our work detailing cryoEM of nitrogenase under catalytic turnover conditions! This collaborative work has enabled the structural characterization of the nitrogenase reaction intermediates at high resolution for the first time. biorxiv.org/content/10.110…
First, I want to say it has been an amazing collaboration with @HannahRutrut (now Ph.D.!), @BCryoEM, @HoangPMNguyen, and @TezcanLab. We paired the best of our strengths to tackle this technically challenging project. Lots of exciting and unexpected results. #teamnitro
Reduced forms of nitrogen are essential for sustaining life. They are required for the biosynthesis of amino and nucleic acids as well as the production of commodity chemicals and fertilizers. Although life can exist without oxygen, life cannot exist without nitrogen.
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