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This new preprint by Stadler et al. integrated data from 37 randomized controlled trials to ask how the timing and dose of passive antibodies (monoclonal Ab & convalescent plasma) predict protection from SARS-CoV-2 disease. A short 🧵 (1/)

medrxiv.org/content/10.110…
Timing: the study found that the earlier the patients were treated with monoclonal antibodies (mAb) or convalescent plasma (CP), the more effective the passive antibodies were in preventing the clinical outcome measured (indicated by right end of line). #TheEarlierTheBetter (2/)
These data are reminiscent of endogenously induced antibody responses against SARS-CoV-2. In patients with fatal COVID, the onset of antiviral antibodies was significantly delayed compared to those who survived COVID. @carolilucas @sneakyvirus1 (3/)

nature.com/articles/s4159…
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