Discover and read the best of Twitter Threads about #tigit

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The #AACR23 abstracts will be accessible from here (not all sessions populated yet at the time of this tweet)
abstractsonline.com/pp8/#!/10828/
"new drugs on the horizon":

ND03 - Discovery of ARV-766, an androgen receptor degrading PROTAC for the treatment of men with metastatic castration resistant prostate cancer $ARVN #PROTAC
abstractsonline.com/pp8/#!/10828/p…
ND01 - ABBV-319: A first-in-class Glucocorticoid Receptor Modulator (GRM) agonist #ADC for the treatment of B-cell malignancies $ABBV
abstractsonline.com/pp8/#!/10828/p…
Read 42 tweets
#ESMO20 Presentation of the phase II PRINCEPS trial of neoadjuvant atezolizumab monotherapy in resectable NSCLC by @BenjaminBesseMD from @GustaveRoussy #LCSM @OncoAlert @myESMO Image
#ESMO20 Building on other studies showing 17-45% rates of major pathologic responses (MPR) but focused on the translational opportunities with these neoadjuvant trials #LCSM @OncoAlert Image
#ESMO20 In the PRINCEPS trial, only a single dose of atezolizumab was given 3 weeks before resection. Focused on safety (2m tolerance) with plans for 60 patients. As it became clear from other studies that this was a safe approach, sample size dropped to 30 (+ 30 control). #LCSM ImageImageImageImage
Read 8 tweets

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