Discover and read the best of Twitter Threads about #transplantation
Most recents (13)
[World #IBSAwarenessMonth] Dear #HCPs👩⚕️ & #Microbiota community👨🔬, April is dedicated to raising awareness about #IrritableBowelSyndrome
During the month, @Microbiota_Inst will provide you with content about #IBS, a common & complex #disease
#GutHealth #LetsTalkIBS #thread👇
During the month, @Microbiota_Inst will provide you with content about #IBS, a common & complex #disease
#GutHealth #LetsTalkIBS #thread👇
[World #IBSAwarenessMonth]
🔎 You will:
👉better understand the🔗between #IBS & #microbiota
👉discover potential ways to manage the #disease
👉learn to make a #diagnosis with our #CME courses, #videos & a professionally designed #tool
👉improve communication with your #patients
🔎 You will:
👉better understand the🔗between #IBS & #microbiota
👉discover potential ways to manage the #disease
👉learn to make a #diagnosis with our #CME courses, #videos & a professionally designed #tool
👉improve communication with your #patients
[World #IBSAwarenessMonth]
1️⃣ In this sequence, learn more about the link between #microbiota and #IrritableBowelSyndrome.
#IBS #MedTwitter #GITwitter #GutHealth #LetsTalkIBS #DGBI #FGID #GIfellows #TakeIBSSeriously
Take a look! 👇
1️⃣ In this sequence, learn more about the link between #microbiota and #IrritableBowelSyndrome.
#IBS #MedTwitter #GITwitter #GutHealth #LetsTalkIBS #DGBI #FGID #GIfellows #TakeIBSSeriously
Take a look! 👇
@EU_Commission @IntlCrimCourt Children of #Donbass - THE #WAR IS ON! CHILDREN vs THE #NAZIS | 5 months ago
rumble.com/v1odju5-childr…
#SaveOurChildren deNAZIfication - Special Military QperationZ WORLDWIDE
rumble.com/v1odju5-childr…
#SaveOurChildren deNAZIfication - Special Military QperationZ WORLDWIDE
@EU_Commission @IntlCrimCourt cc: @ DaniMayakovski
#Ukraine. Images from the #Azov Battalion children's camp, where children from the age of 8 are #brainwashed into #Nazism and prepared militarily by indoctrinating them into a #hatred of #killing Russians. (2015)
#Ukraine. Images from the #Azov Battalion children's camp, where children from the age of 8 are #brainwashed into #Nazism and prepared militarily by indoctrinating them into a #hatred of #killing Russians. (2015)
@EU_Commission @IntlCrimCourt Ukrainian children drugged and indoctrinated by the #Nazis into shouting the #Hitler salute of "#SiegHeil" while being laughed at. (2016)
This video was captured from the flash drive of a press reporter from the #AzovBattalion at the #Mariupol base.
This video was captured from the flash drive of a press reporter from the #AzovBattalion at the #Mariupol base.
A new milestone 🎉: my 3⃣0⃣th publication!
Published @amjtransplant, entitled:
"An interleukin 6-based genetic risk score strengthened with interleukin 10 polymorphisms associated with long-term #kidney allograft outcomes."
➡️pubmed.ncbi.nlm.nih.gov/36453708/
Time for a #tweetorial 🧵👇
Published @amjtransplant, entitled:
"An interleukin 6-based genetic risk score strengthened with interleukin 10 polymorphisms associated with long-term #kidney allograft outcomes."
➡️pubmed.ncbi.nlm.nih.gov/36453708/
Time for a #tweetorial 🧵👇
1.) Of all #kidney transplants, half are still lost in the first decade after #transplantation.
Using #genetics 🧬, we probed if interleukin 6 (IL-6) could be a target in kidney #transplantation to improve graft survival & if a genetic risk score could improve prognostication.
Using #genetics 🧬, we probed if interleukin 6 (IL-6) could be a target in kidney #transplantation to improve graft survival & if a genetic risk score could improve prognostication.
2.) Together with @marigaya, @VojtechPetr and colleagues from the @GTCumcg & @researchumcg, we studied the impact of IL6, IL6R, IL10, IL10RA & IL10RB 🧬variants on late graft loss by analyzing both recipient and donor DNA of >1,200 #kidney transplant‐pairs.
@YAGroningen @umcg
@YAGroningen @umcg
Την έλεγαν Έμα, βγαίνει απτο Εμμανουέλα.
Μάλλον τον παππού της τον έλεγαν Μανώλη.
Ηταν μονο 21 ετών, σπούδαζε Κτηνίατρος
στο ΑΠΘ.
Περπατούσε στο ύψος της Καμάρας στην Εγνατία
και παρασύρθηκε απο εναν ασυνείδητο οδηγό
οποίος δραπέτευσε,
Μάλλον τον παππού της τον έλεγαν Μανώλη.
Ηταν μονο 21 ετών, σπούδαζε Κτηνίατρος
στο ΑΠΘ.
Περπατούσε στο ύψος της Καμάρας στην Εγνατία
και παρασύρθηκε απο εναν ασυνείδητο οδηγό
οποίος δραπέτευσε,
δεν κάλεσε ασθενοφόρο,δεν έσκυψε
να δει αν ζει,δεν,δεν,δεν
Όπως πετάμε μια τσίχλα, ένα χαρτάκι και δεν κοιτάμε πίσω.
Φοβήθηκε λέει,δε το θελε,ηταν η κακιά η ώρα.
Αν διέσχιζε τη διάβαση
θα ζούσε λέει..
τόσο προκλητικός.
Φοβήθηκε 26 ετών μλκς
και η συνοδηγός κι αυτή ολίγιστη.
να δει αν ζει,δεν,δεν,δεν
Όπως πετάμε μια τσίχλα, ένα χαρτάκι και δεν κοιτάμε πίσω.
Φοβήθηκε λέει,δε το θελε,ηταν η κακιά η ώρα.
Αν διέσχιζε τη διάβαση
θα ζούσε λέει..
τόσο προκλητικός.
Φοβήθηκε 26 ετών μλκς
και η συνοδηγός κι αυτή ολίγιστη.
Μάλιστα, έκανε όπισθεν και τη χτύπησε δεύτερη φορά εγκαταλείποντας βαριά τραυματισμένη
στην άσφαλτο.
Ώρες μετά ξεφορτώθηκε τον αριθμό των πινακίδων κυκλοφορίας πριν τον κόμβο Ασβεστοχωρίου.
Αφού παρήλθε το
48ωρο αυτόφωρο,
ο ίδιος παρουσιάστηκε
την Πέμπτη ενώπιον της ΕΛ.ΑΣ.
στην άσφαλτο.
Ώρες μετά ξεφορτώθηκε τον αριθμό των πινακίδων κυκλοφορίας πριν τον κόμβο Ασβεστοχωρίου.
Αφού παρήλθε το
48ωρο αυτόφωρο,
ο ίδιος παρουσιάστηκε
την Πέμπτη ενώπιον της ΕΛ.ΑΣ.
Self-organizing systems have been one of the most exciting recent advances in stem cell research
However, many names & classifications are used making it challenging to convey the science
We now got together as a field to provide a nomenclature framework
Out in @Nature today👇1/9
However, many names & classifications are used making it challenging to convey the science
We now got together as a field to provide a nomenclature framework
Out in @Nature today👇1/9
We focused on neural #organoids #assembloids & #transplantation
Our consensus is summarized in one simple figure (above) & a short text box 👇
Our consensus is summarized in one simple figure (above) & a short text box 👇
#transplantation
We’re just 50 days into 2022, and already…
Nuclear fusion saw another major breakthrough… a ‘huge step’ in the quest for clean energy.
A woman was cured of HIV through a breakthrough stem cell treatment.
We’re just 50 days into 2022, and already…
Nuclear fusion saw another major breakthrough… a ‘huge step’ in the quest for clean energy.
A woman was cured of HIV through a breakthrough stem cell treatment.
MIT engineers created an ‘impossible’ new material… stronger than steel but as light as plastic.
An international team of scientists used supercomputers to unlock a ‘giant leap’ in the fight against antibiotic resistance.
An international team of scientists used supercomputers to unlock a ‘giant leap’ in the fight against antibiotic resistance.
A new ‘game-changing’ carbon capture technology could deliver a step change in our ability to remove carbon dioxide from the air.
We are lucky to have @DineeMD teach us about structural racism and health inequities in #transplantation and more importantly how she is leading the way to change this with her team! @Penn_Transplant @nutorc @KimOlthoff @LevineTxpSurg @EmilyBlumbergMD @nadimmahmud
Images of Infectious Diseases
6 mo post-tx: H&E (400x) of cervical biopsy of 46F s/p living unrelated donor kidney tx for adult PCKD.
Belatacept. MMF. Prednisone.
Acute cellular + antibody-mediated rejection.
CMV D+/R-. valganciclovir prophylaxis.
DDx / Rx? #MayoIDQ next
6 mo post-tx: H&E (400x) of cervical biopsy of 46F s/p living unrelated donor kidney tx for adult PCKD.
Belatacept. MMF. Prednisone.
Acute cellular + antibody-mediated rejection.
CMV D+/R-. valganciclovir prophylaxis.
DDx / Rx? #MayoIDQ next
2/
Case diagnosis: breakthrough CMV disease with cervicitis
H&E intranuclear / intracytoppasmic inclusions within endothelial cells in ectocervical stroma.
Immunohistochemistry stain for CMV shows infected endothelial cells with CMV inclusions.
doi.org/10.1111/tid.13…
Case diagnosis: breakthrough CMV disease with cervicitis
H&E intranuclear / intracytoppasmic inclusions within endothelial cells in ectocervical stroma.
Immunohistochemistry stain for CMV shows infected endothelial cells with CMV inclusions.
doi.org/10.1111/tid.13…
3/
#MayoIDQ Breakthrough CMV disease, while receiving valGCV prophylaxis, is concerning for over-immunosuppression, under-dosing of val GCV, and/or drug-resistant virus.
If gene sequencing shows the most common CMV gene mutation, what drug would be recommended Rx?
#MayoIDQ Breakthrough CMV disease, while receiving valGCV prophylaxis, is concerning for over-immunosuppression, under-dosing of val GCV, and/or drug-resistant virus.
If gene sequencing shows the most common CMV gene mutation, what drug would be recommended Rx?
I request Punjab CM @capt_amarinder to prepone the paddy transplantation season to June 1 by removing the ban on transplantation of paddy till June 15 keeping in view of the severe labour shortage due to return of migrant labour to Uttar Pradesh and Bihar. 1/3
#lockdownindia
#lockdownindia
I would also urge CM to exponentially increase #paddy transplantation machines in the State to increase mechanisation so that the labour shortage could be offset to some extent. And for the farmers willing to purchase this machinery should be given 75 % subsidy. 2/3
Further, sensing the situation State government should also permit #transplantation of PUSA 44 paddy variety which is being disallowed on the pretext that it takes 20 to 22 days more to mature than other varieties leading to high moisture content later. 3/3
#lockdown #Punjab
#lockdown #Punjab
(1/3) Amazing case study in the American Journal of #Transplantation:
A kidney #transplant patient was being treated for metastatic cancer using a checkpoint inhibitor, which caused the patient's immune system to reject the kidney (...)
onlinelibrary.wiley.com/doi/abs/10.111…
A kidney #transplant patient was being treated for metastatic cancer using a checkpoint inhibitor, which caused the patient's immune system to reject the kidney (...)
onlinelibrary.wiley.com/doi/abs/10.111…
(2/3) After experiencing a complete response, the patient was re-transplanted with a second kidney. This second graft was monitored for rejection using a novel #liquid #biopsy.
This is the first time, to my knowledge, a patient beat cancer and active organ rejection.
This is the first time, to my knowledge, a patient beat cancer and active organ rejection.
(3/3) We think liquid biopsies will fundamentally change the transplant space, allowing doctors to precisely dial #immunosuppressive medication, anticipate organ rejection, and monitor organ health, using a non-invasive approach.
🤓Here are our lecture presentations for #DDW2020
1/1 #Gut #microbiota and role in clinical events & #treatment response in #alcoholic #hepatitis. LEfSE, Conet and NetworkX analysis.
@AASLDtweets @DDWMeeting @AmerGastroAssn #medtwitter #MedEd #AcademicTwitter
1/1 #Gut #microbiota and role in clinical events & #treatment response in #alcoholic #hepatitis. LEfSE, Conet and NetworkX analysis.
@AASLDtweets @DDWMeeting @AmerGastroAssn #medtwitter #MedEd #AcademicTwitter
1/
Hi hi hi. We see lots of red flags on a daily basis when we review labs.
One thing we see commonly is #lymphopenia. Should we care? When can we dismiss it and when should we work it up?
Let’s find out.
#MedEd #MedTwitter #IDTwitter #Tweetorial #oncology
Hi hi hi. We see lots of red flags on a daily basis when we review labs.
One thing we see commonly is #lymphopenia. Should we care? When can we dismiss it and when should we work it up?
Let’s find out.
#MedEd #MedTwitter #IDTwitter #Tweetorial #oncology
2/
- Lymphopenia assc w/ ⬆️risk of sepsis
- More common in elderly and w/ co-morbidities
- lymphs account for 20-40% of WBC, may go unnoticed when WBC checked w/o diff
- Primary- recurrent infxns in kids, CVID in adults
- Secondary-⬇️production; ⬆️destruction; hiding in tissue
- Lymphopenia assc w/ ⬆️risk of sepsis
- More common in elderly and w/ co-morbidities
- lymphs account for 20-40% of WBC, may go unnoticed when WBC checked w/o diff
- Primary- recurrent infxns in kids, CVID in adults
- Secondary-⬇️production; ⬆️destruction; hiding in tissue
3/
What is the most common cause of lymphopenia in hospitalized patients?
What is the most common cause of lymphopenia in hospitalized patients?
1/ A short #tweetorial introducing human leukocyte antigen (HLA) and typing...an important and often confusing topic in #transplantation #kidneytransplant
#FOAMed @MedTweetorials
What is an "HLA"?
#FOAMed @MedTweetorials
What is an "HLA"?
2/
HLAs = cell surface proteins encoded by highly polymorphic major histocompatibility complex (MHC) genes on Ch 6 🧬
In #transplantation, HLA proteins are #polymorphic antigens ➡️ alloreactive trigger for the immune response ➡️ can ultimately lead to organ #rejection ☠️
HLAs = cell surface proteins encoded by highly polymorphic major histocompatibility complex (MHC) genes on Ch 6 🧬
In #transplantation, HLA proteins are #polymorphic antigens ➡️ alloreactive trigger for the immune response ➡️ can ultimately lead to organ #rejection ☠️
3/ The 2 primary classes of MHC molecules are 1⃣ and 2⃣.
Class 1⃣ MHC are found on the cell surface of ALL nucleated cells + platelets. Their role is to present intracelleular peptide fragments to CD8 #Tcells
Class 1⃣ MHC are found on the cell surface of ALL nucleated cells + platelets. Their role is to present intracelleular peptide fragments to CD8 #Tcells
