Discover and read the best of Twitter Threads about #tresamigos

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Finally got to analyze & put my thoughts together on the recent #posaconazole vs. #voriconazole phase 3 trial for invasive #aspergillosis published in .@TheLancet a few weeks ago.
Best is to put the major trials of the 3 #VIP triazoles done over the last 20 years in perspective!
Here is the table with key points of trial design of the #TresAmigos trials, interesting features:

#Vori-Ampho was open label, but with blinded adjudication, including to adverse effects.

All where non-inferiority trials, #vori-amphoB had a clause for claiming superiority.
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