Discover and read the best of Twitter Threads about #tripleMutant
Most recents (1)
So much misinformation and confusion about the circulating #SARSCoV2 variants in India. Leaving aside that the names are scientifically inaccurate, #B1618 ("Bengal variant") is NOT the #tripleMutant. I will try to summarize the basics in this thread.
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B.1.617: characterized by more than 15 mutations, it got dubbed the "double mutant" because of two spike mutations, L452R and E484Q, which were mutations of concern because of their immune escape properties, and possible high infectivity.
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What's more, there are several sequences of B.1.617 which don't have the E484Q mutation, now sampled in India and elsewhere, which means it's not even the OG "double mutant" anymore.
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