Discover and read the best of Twitter Threads about #trivalent

Most recents (1)

Profile picture
David R. Martinez, Ph.D.
@David_RMartinez
Our latest paper describing #universal #CoV vaccine that can protect against #MERSCoV and #SARSCoV is now out⁩ in #preprint ⁦@YaleMed⁩ ⁦

Short thread 👇🏼

“Vaccine-mediated protection against merbecovirus and sarbecovirus challenge in mice” biorxiv.org/content/10.110…
We were interested in developing vaccination strategies against highly pathogenic human #coronaviruses with epidemic potential. Our previous studies, and those of others, defined the #RBD as a major target of neutralizing antibodies.
We therefore looked to #ferritin nanoparticles as a scaffold to display genetically divergent RBDs from both Group 2c merbecoviruses (#MERSCoV) and Group 2b sarbecoviruses (#SARSCoV , #SARSlike viruses, and #SARSCoV2). Our vaccines elicited broad binding antibodies in mice.
Read 6 tweets

Related hashtags

#MERSCoV #nanoparticle #RBD #preprint #SARSCoV #universal #trivalent #SARSCoV2 #ferritin #SARSlike #coronaviruses #CoV

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!