Discover and read the best of Twitter Threads about #tweetorialera
Most recents (3)
💥Membranous Nephropathy (MN); New antigens, new disease?
#tweetorialERA #membranous #nephtwitter #FOAMed #tweetorial
#tweetorialERA #membranous #nephtwitter #FOAMed #tweetorial
MN occurs due to immune complex deposition in the subepithelial GBM. @SethiRenalPath reckons classification of MN should be made based on the antigen, much like the nomenclature of complement activated GN following better understanding of the role of complement dysregulation.
☄️Hot off the press review suggesting we should consider MN as a pattern of injury. @SethiRenalPath @CKJsocial
🔍Let's take a look at the discovery of antigens in MN.
academic.oup.com/ckj/advance-ar…
🔍Let's take a look at the discovery of antigens in MN.
academic.oup.com/ckj/advance-ar…
⏳for another #tweetorialERA 🥳 @HDiniz_
➡️Native kidney biopsy plays a crucial role in the diagnosis of many conditions and, while generally safe, can be associated with bleeding complications.
Would you biopsy a patient with aspirin exposure?🤔
➡️Native kidney biopsy plays a crucial role in the diagnosis of many conditions and, while generally safe, can be associated with bleeding complications.
Would you biopsy a patient with aspirin exposure?🤔
Bleeding complication rates are low, with less than 2% of patients requiring transfusion and less than 0.5% requiring an intervention to control the bleeding.
⚠️These complication rates are higher in hospitalized patients and those with AKI.
cjasn.asnjournals.org/content/15/11/…
⚠️These complication rates are higher in hospitalized patients and those with AKI.
cjasn.asnjournals.org/content/15/11/…
But not every patient has the same risk of bleeding 🩸
Risk factors include anemia, thrombocytopenia, frailty index, obesity, comorbidities, and kidney function.
cjasn.asnjournals.org/content/15/11/…
Risk factors include anemia, thrombocytopenia, frailty index, obesity, comorbidities, and kidney function.
cjasn.asnjournals.org/content/15/11/…
Time for a tweetorial on renal MRI! MRI is used to look at structure, but advanced sequences can measure function too. Multiple sequences in 1 session = multiparametric MRI = loads of data!
Could be used to triage risk in CKD, reduce invasive tests, or for translational research
Could be used to triage risk in CKD, reduce invasive tests, or for translational research
An imaging biomarker is already being used in clinical practice. For which condition?
It's ADPKD! 🙌🙌🙌
Total kidney volume is approved by the FDA to identify patients at high risk of progressive renal impairment to treat with tolvaptan. TKV is best measured by kidney MRI and evaluated using the Mayo classification
Total kidney volume is approved by the FDA to identify patients at high risk of progressive renal impairment to treat with tolvaptan. TKV is best measured by kidney MRI and evaluated using the Mayo classification
