Discover and read the best of Twitter Threads about #v2f

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Are you interested in how we can learn more human biology by integrating #singlecell genomics and #GWAS?

Please check out our preprint:
#V2F mapping at single-cell resolution through network propagation

biorxiv.org/content/10.110…

Led by @fulong_yu! A short 🧵 (1/n)
#GWAS have identified innumerable variants associated with disease, as shown in this recent @GWASCatalog plot, yet our understanding of the function of most variants is lacking. #V2F (2/n)
With the increasing availability of #singlecell genomic atlases, such as the @humancellatlas, there are tremendous opportunities to systematically map variants to functional regulatory elements, which can be defined by accessible chromatin or epigenomic marks. (3/n)
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