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New pre-print!
A novel Axin2 knock-in mouse model for visualization and lineage tracing of WNT/CTNNB1 responsive cells
Shared 1st authors @AnoeskaMoosdijk & Yorick van de Grift, with critical contributions by @Saskia_deMan & Amber Zeeman.
biorxiv.org/content/10.110…
Details ⬇️
A novel Axin2 knock-in mouse model for visualization and lineage tracing of WNT/CTNNB1 responsive cells
Shared 1st authors @AnoeskaMoosdijk & Yorick van de Grift, with critical contributions by @Saskia_deMan & Amber Zeeman.
biorxiv.org/content/10.110…
Details ⬇️
Who would be interested?
#Wnt aficionados, developmental biologists and stem cell biologists who are interested in visualizing and tracking populations of WNT/CTNNB1 responsive cells.
#Wnt aficionados, developmental biologists and stem cell biologists who are interested in visualizing and tracking populations of WNT/CTNNB1 responsive cells.
What's new?
This model combines a fluorescent reporter (so cells with active WNT/CTNNB1 signaling can be directly visualized) with a lineage tracing driver (so these cells can also be permanently labeled and tracked to see what happens to their offspring).
This model combines a fluorescent reporter (so cells with active WNT/CTNNB1 signaling can be directly visualized) with a lineage tracing driver (so these cells can also be permanently labeled and tracked to see what happens to their offspring).
