Discover and read the best of Twitter Threads about #xdr

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Emergence of extensively drug-resistant (XDR) and multidrug-resistant (MDR) #Shigella flexneri serotype 2a associated with #sexual transmission among men who have sex with men (MSM), in #England: a descriptive epidemiological study
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thelancet.com/journals/lanin…
In this study, authors report the emergence and sustained transmission of #XDR and #MDR strains of S flexneri among among MSM, harbouring plasmid-encoded blaCTX-M-27, in England since September, 2021.

There were clinically severe cases, including hospitalisations.
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Comparison to the XDR S. sonnei outbreak revealed epidemiological and #plasmid similarities and provided support for horizontal acquisition events in a community transmitting infection.
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