Discover and read the best of Twitter Threads about #zoledronicacid

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As the year ends, it's time once again to discuss some of the best clinical papers in the 🦴 #bone field in 2022!

A long 🧵
@Sandroppa @ECTS_science @larsfolkestad
Nr. 1: Supplemental #VitaminD and Incident #Fractures in Midlife and Older Adults @NEJM

No effect in the VITAL trial although confidence intervals do not exclude meaningful reduction in patients on osteoporosis meds or with fracture history

nejm.org/doi/full/10.10…
#VitaminD Deficiency Increases Mortality Risk in the UK Biobank
A Nonlinear Mendelian Randomization Study

Risk increased steeply < 50 nmol/L and was greater with genetic than phenotypic vitamin D deficiency
@AnnalsofIM
acpjournals.org/doi/10.7326/M2…
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