Max Konig Profile picture
Rheumatologist/Assistant Prof @JohnsHopkins | via Berlin & Boston | Cellular therapies; Bispecific antibodies; Antigen-specific therapies for rheumatic diseases

Nov 11, 2019, 13 tweets

Path in GPA vs RP

Relapsing polychondritis criteria #ACR19

Absence of typical manifestation of RP such as saddle nose deformity, ear inflammation, and subglottic stenosis does not exclude, but delays Dx #ACR19

ANCA positivity in up to 25% of patients with RP. Anti-collagen II antibodies are not sensitive and may only be positive in active disease.

How to workup relapsing polychondritis:

Differential of auricular inflammation @philseo #ACR19

Differential diagnosis of saddle nose deformity

@philseo How to treat relapsing polychondritis

Pear: In #GPA, nasal septum perforation precedes nasal bridge collapse, while nasal bridge can collapse in isolation and without warning in #relapsingpolychondritis #ACR19

*Pearl

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