Path in GPA vs RP 
Relapsing polychondritis criteria #ACR19
Absence of typical manifestation of RP such as saddle nose deformity, ear inflammation, and subglottic stenosis does not exclude, but delays Dx #ACR19
ANCA positivity in up to 25% of patients with RP. Anti-collagen II antibodies are not sensitive and may only be positive in active disease.
How to workup relapsing polychondritis:
Differential diagnosis of saddle nose deformity
@philseo How to treat relapsing polychondritis
Pear: In #GPA, nasal septum perforation precedes nasal bridge collapse, while nasal bridge can collapse in isolation and without warning in #relapsingpolychondritis #ACR19
*Pearl
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