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Nov 24, 2019, 5 tweets

ID Miscellany|Exams|Signs|Humanities #idmesh

1/5
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Unusual pattern of sensory loss in neurosyphilis (tabes dorsalis):

β–ͺ️ central face (tip of nose)
β–ͺ️ band on the trunk (nipple area)
β–ͺ️ medial forearms (when ulnar nerve pressed at elbow)
β–ͺ️ lateral leg

2/5
It is a physical exam finding lost in antiquity.

Tabes dorsalis was the most common form of neurosyphilis in the pre-antibiotic era but today, it is extremely rare (longest latency period between primary infection & SSx).

karger.com/Article/FullTe…

3/5
Tabes dorsalis involves posterior columns/dorsal roots.

β–ͺ️ wide-based gait, foot slap (worse in the dark)
β–ͺ️ +Rombergs, absent knee/ankle DTRs
β–ͺ️ vibration/proprio loss
β–ͺ️ lancinating paints
β–ͺ️ Charcot joint/ulcer
β–ͺ️ Argyll-Robterson pupil (another #idmesh topic)

4/5
Named after Eduard Hitzig (6 February 1838 – 20 August 1907), a German neurologist & neuropsychiatrist who was one of the first people to map out the motor and sensory areas of the brain.

5/5
The archived section of our medial libraries probably has the best resources on tabes dorsalis. But here is one from Google, published in 1936:

google.com/url?sa=t&rct=j…

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