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Dec 1, 2019, 7 tweets

ID Miscellany|physical Exam|Signs|Humanities #idmesh

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π„π©π’π­π«π¨πœπ‘π₯𝐞𝐚𝐫 𝐍𝐨𝐝𝐞𝐬

Palpating for the epitrochlear nodes is an exam that I like to teach at bedside. When palpable, these nodes often indicate a condition characterized by generalized lymphadenopathy.

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Epitrochlear nodes (EN) are superficial nodes located 2-3 cm above and anterior to the medial condyle of the humerus.

Exam: shake patient's hand, on the side to be examined; examiner's free hand palpates for ENs πŸ‘‡

Pics from:
aafp.org/afp/2016/1201/…
memorangapp.com/flashcards/802…

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ENs drain the ulnar forearm & the little/ring fingers.

Enlarged ENs are rare in healthy individuals (no more than few millimeters in size).

Unilateral enlargement can indicate localized cutaneous infection/malignancy/inflammation of the forearm/hands.

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π’π²π¦π¦πžπ­π«π’πœ 𝐞𝐧π₯𝐚𝐫𝐠𝐞𝐦𝐞𝐧𝐭 indicates a condition characterized by generalized LAD.

Historically, a/w secondary syphilis (at least 1/2 of cases).
jamanetwork.com/journals/jamad…
sciencedirect.com/science/articl…

Osler's two-handed hand-elbow salutation:
bmj.com/rapid-response…

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They can also be seen in:

β–ͺ️ Mononucleosis & HIV (>50%)
β–ͺ️ Lymphoma, CLL, sarcoidosis (30%)
β–ͺ️ Rheumatoid arthritis (20%)

ncbi.nlm.nih.gov/pubmed/1588523

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A more recent review, however, shows us a wider range of disease associations πŸ‘‡.

This review also identified:

β–ͺ️ leprosy as most commonly associated pre-HIV
β–ͺ️ HIV +/- TB, HIV pre-HAART era
β–ͺ️ cat-scratch disease, most common infection post-HAART

ncbi.nlm.nih.gov/pmc/articles/P…

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Do you routinely palpate for epitrochlear nodes in your practice? Have you had opportunities that demonstrated its utility? Please feel free to leave your comments.

@AndreMansoor @DxRxEdu @TxID_Edu @BradCutrellMD @DocWoc71 @Darcy_ID_doc @MohitHarshMD

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