Edgar V. Lerma 🇵🇭 Profile picture
Chicago Sports Fan... Nephrologist by day. My tweets are not medical advice. The views expressed here are my own and not those of my employer.

Jan 29, 2020, 10 tweets

Risk of Nephrogenic Systemic Fibrosis in Patients With Stage 4 or 5 Chronic Kidney Disease Receiving a Group II Gadolinium-Based Contrast Agent: A Systematic Review and Meta-analysis ca. 2019
#VisualAbstract by @VickiSandys1
#NephJC #Nephpearls
👉🏼 jamanetwork.com/journals/jamai…

Chart showing cumulative Nephrogenic Systemic Fibrosis (NSF) cases reported to the NSF Registry by date of onset through 2012
📌 Important FDA announcements are marked on the timeline
#Nephpearls #NephJC

Depiction of the current gadolinium-based contrast agents approved for clinical use in Canada 🇨🇦 #Nephpearls #NephJC
👉🏼 ncbi.nlm.nih.gov/pmc/articles/P…

Which is WORSE ⁉️ Risk of Gadolinium Nephrotoxicity or Radiocontrast Nephropathy #Nephpearls #NephJC #AskRenal

On GADOLINIUM and the Kidney
1⃣ Nephrogenic Systemic Fibrosis
2⃣ AKI
3⃣ Pseudohypocalcemia
#Nephpearls #NephJC
👉🏼 ncbi.nlm.nih.gov/m/pubmed/18033…

In this illustration, a nonionic linear chelate (gadodiamide), which binds Gd3􏰁 less tightly than other chelates (macrocyclic and ionic), is shown undergoing the process of transmetallation #Nephpearls #NephJC
👉🏼 cjasn.asnjournals.org/content/clinja…

Nephrogenic Systemic Fibrosis: Differential Diagnosis #Nephpearls #NephJC
👉🏼 mdedge.com/ccjm/article/9…

Nephrogenic Systemic Fibrosis: Prevention and Treatment from @NephRodby’s lecture
#NKFClinicals 2019 #Nephpearls #NephJC
👉🏼 ncbi.nlm.nih.gov/m/pubmed/17555…

Although Nephrogenic Systemic Fibrosis occurrence after exposure to newer GBCAs is very rare, the relatively scarce data among patients w/ AKI and those w/ risk factors for CKD limit conclusions about safety‼️ (ca. 2020) from @AnnalsofIM #Nephpearls
👉🏼 acpjournals.org/doi/pdf/10.732…

Risks and Options With Gadolinium-Based Contrast Agents in Patients With CKD: A Review ca. 2020 from @AJKDonline @MichaelRudnick7 #Nephpearls
👉🏼 ajkd.org/action/showPdf…

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