Thread by @chitguppi

Thread:
Effect of Chlorhexidine CHX on coronavirus:

CHX concentration tested in various studies till now has been too low.
1st study: CHX 0.02% w/v (1988)
2nd study: 0.01125- 0.015 % w/v (1998)
These conc. are too low & these studies didn't test CHX against coronavirus either

When Hong Kong University researchers increased the Chlorhexidine concentration by just three units i.e. from 0.02% to 0.05% CHX was found to be effective against the coronavirus. CHX was found to be as effective as 7.5% Povidone Iodine or 70% ethyl alcohol.

Hence dental & medical practitioners need not worry about Chlorhexidine gluconate being ineffective against the novel Coronavirus. The concentrations used in the earlier experiments are too low, and worse, they were not even tested against the novel coronavirus.

The CHX conc. tested in early experiments (< 0.02%) was so low that currently no CHX products are available in such low conc.

CHX mouthwashes available in the market (0.12% & 0.2%) now are 2- 4 times more conc. than the CHX conc. that inactivates the novel coronavirus (0.05%).

Chlorhexidine alcohol based hand rubs (0.5% w/v) are TEN times more concentrated than what is needed (0.05%) to inactivate the novel coronavirus.

Chlorhexidine hand scrubs (4% w/v) are EIGHTY times more concentrated than what is needed to inactivate the novel coronavirus.

It means Chlorhexidine is very much effective against novel coronavirus. Hong Kong University study published in The Lancet Microbe says "0.05% CHX works as good as 7.5% Povidone Iodine or 70% Ethyl Alcohol"

So where is the question of CHX being ineffective against coronavirus?

All concerned #Dentistry #Periodontics authorities @AmerDentalAssn @AmerAcadPerio @PerioEurope @fdiworlddental @WHO @CDCgov @CDC_NCEZID @USPharmacopeia @The_BDJ should come up with a statement on the efficacy & effectiveness of Chlorhexidine against novel coronavirus #SARS_COV_2

There has been some serious misinterpretation of study results. With the latest study by @hkumed showing that Chlorhexidine is as effective as Povidone Iodine & Ethyl alcohol [even in very low (0.05%) conc.] there is an urgent need to inform dentists & medical practitioners.

To read my analysis of all studies published till now on the topic "Effect of Chlorhexidine on Coronavirus" please download my article from Researchgate. Points to the exact reason why there is a misconception & what should be the correct interpretation
researchgate.net/publication/34…