Nasal immunization could be the most efficient and potentially least harmful against coronaviruses, in line with the primary role of the mucosal barrier in providing protection. cell.com/immunity/fullt…
“mortality in 12- to 22-month-old mice infected with SARS-CoV or IAV was reduced from 80 to 100% to 0 to 10% by treatment with a TLR3 agonist, poly(I·C), with concomitant increased expression of interferon (IFN) and other proinflammatory molecules”
jvi.asm.org/content/86/21/…
Looking at systemic antibody levels in connection with respiratory infections is counterproductive. Let’s focus on healthy physiology/basic (mucosal) immunology, instead of centering on traditional vaccinations.
jvi.asm.org/content/77/21/…
Here we go
https://t.co/zRJXMYV91w
As expected? I love when theoretical science is verified by experiments. Thx @BillOccham
biorxiv.org/content/10.110…
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