Prof Chris P Gale Profile picture
Professor of Cardiovascular Medicine, Honorary Consultant Cardiologist. Specialist adult cardiovascular care: putting research into practice to benefit patients

Aug 31, 2020, 7 tweets

‘Overall, #antiplatelet monotherapy is ineffective for #stroke prevention [for #AtrialFibrillation] & potentially harmful (especially #elderly), whereas #DAPT associated with bleeding risk similar to OAC. Hence, antiplatelets should not be used for #stroke prevention in #AF

2020 ESC Guidelines for the diagnosis and management of #AtrialFibrillation #ESCCongress : academic.oup.com/eurheartj/adva…

‘Between 2009 & 2018, in #England, the use of #OAC for #stroke prophylaxis in #AtrialFibrillation increased, with #DOAC accounting for over half of OAC uptake in 2018.’

‘Despite a reduction in the OAC-prescription gap, a new paradox exists relating to #DOAC prescription for the #elderly & those at higher risk of #stroke.’

Temporal trends in #stroke prophylaxis for #AtrialFibrillation

Temporal trends in #DOAC prescription for #stroke prophylaxis in #AtrialFibrillation, by age. #elderly

Prescription of oral #anticoagulants & #antiplatelets for #stroke prophylaxis in #AtrialFibrillation : nationwide time series ecological analysis @ESC_Journals academic.oup.com/europace/advan…

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