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Sep 28, 2020, 5 tweets

NEW—Radiotherapy following prostate cancer surgery can safely be avoided for many men: finding from a prospectively planned systematic review & meta-analysis assessing results from 2153 men enrolled across 3 trials, with median follow-up of at least 5 yrs hubs.li/H0x3LxP0

NEW—Timing of radiotherapy after radical prostatectomy (RADICALS-RT): a randomised, controlled phase 3 trial hubs.li/H0x5PXH0 (Trial 1/3)

NEW—Adjuvant radiotherapy vs early salvage radiotherapy following radical prostatectomy (TROG 08.03/ANZUP RAVES): a randomised, controlled, phase 3, non-inferiority trial @TheLancetOncol (Trial 2/3) hubs.li/H0x69kT0

NEW—Adjuvant radiotherapy vs early salvage radiotherapy plus short-term androgen deprivation therapy in men with localised prostate cancer after radical prostatectomy (GETUG-AFU 17): a randomised, phase 3 trial
@TheLancetOncol (Trial 3/3) hubs.li/H0x6rpS0

NEW—Timing of radiotherapy after radical prostatectomy

"The studies did not show superiority of adjuvant radiotherapy compared with salvage radiotherapy based on the early endpoint of progression-free survival"

Linked Comment from D Tilki & A V D’Amico hubs.li/H0x6D7F0

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