Pieter Borger Profile picture
P. Borger (MSc, PhD), mol biologist, science writer, author. Defender of science, opponent of pseudoscience. https://t.co/47VTmwQkzz

Apr 8, 2021, 12 tweets

What are DNA vector vaccines?

Astra-Zeneca, but also Jansen Pharma & the Russian Sputnik V are DNA vector vaccines. But what are they and are they dangerous?

DNA vector vaccines are made of DNA viruses, usually Adenoviruses, but with the virulence genes removed.

I believe that there is a potential risk with these vaccines, namely the integration of the DNA vector into the genome. It is negligent to claim, as the EMA does, that the benefit of vaccination is greater than the risk without informing people of the existing long term risks.

It is generally believed that Adenoviruses are harmless to humans: at most, they cause a common cold.

In the DNA vector vaccines that are used to immunise against COVID19, the spike gene of the SARS-CoV-2 has been inserted into the genome of an Adenovirus in the form of DNA.

In this way, the "Spike" gene (DNA containing the information for the spike protein) can be introduced into a human cell and the spike protein can be produced. To understand how this works & where the dangers of DNA vector vaccines lie, we need to better understand this process.

An Adenovirus (on which these DNA vector vaccines are based) has to go to the nucleus of our cells in order to reproduce itself, because only there its DNA can be transcribed into mRNA. Unlike mRNA vaccines, DNA vector vaccines are designed to go to the nucleus on their own.

DNA vector vaccines are thus present in the same compartment as our own DNA.

Statistically speaking, Adenoviruses & the DNA vector vaccines based on them "do not" integrate into the genome. Nevertheless, this happens in a very small percentage: in 1 to 5 per thousand cells.

One per thousand may not seem much, but how many cells/cell nuclei are there in the muscle into which the DNA vector vaccine is injected? And in your body? After vaccination with DNA vector vaccine, surely everyone has a genetically altered cell somewhere in their body.

Hopefully, the genetically altered cell will be recognised and sent into apoptosis (= aborted). If not, over time unexpected neurological, immunological and metabolic abnormalities may occur due to a disturbed genetic context.

DNA vector vaccines have NEVER been tested for this!

We know that DNA virus vaccins integrate in the genome. Therefore, I strongly recommend against vaccination with a DNA vector vaccine. I myself would never voluntarily take these shots.

Doctors, who made the Hippocratic Oath, should read up on the potential dangers of DNA vector vaccins and reread that oath before they start vaccinating people...

For references watch:

For information on RNA vaccines and their potential to integrate in the genome:

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