1/ Still one of my favorite studies in relation to the #LipidEnergyModel. One might wonder what happens to animals who become fat adapted due to fasting for a long period.
Obvious example: Hibernation
#LDL #Cholesterol goes up... does #Atherosclerosis?
pubmed.ncbi.nlm.nih.gov/22686205/
2/ They were comparing bears in captivity and the wild. And in both, lipid levels during hibernation are "considerably higher than what is normally found in humans"
3/ In spite of the high lipid levels alongside other risk factors, they found no signs of atherosclerosis in brown bears.
4/ They actually have some cross sections from autopsy, including LAD...
5/ To be sure, I'd want to add one more possibility to this list below...
... It's possible the scenario of higher ApoB-lipoproteins in the context of fatty acid trafficking is not itself pro-atherogenic. This seems to correlate with human populations that fast regularly as well
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