But I also know many people in my own family who have struggled their whole lives to lose weight and assume if they don't have this near instant drop to their goal weight like <fill in the blank success story> then they are doing it all wrong...
If you've followed me a while, you know I try to avoid the "diet debates" (tho not always successfully)
However, I have been getting a high frequency of DMs/messages/calls regarding DD's new endeavor for a #lowcarb alternative
2/ Let me first start off by saying I don't think any diet is inherently superior to all others.
I *do* think the #lowcarb diet is under-utilized for populations that can uniquely benefit from it.
However, I also believe most of us have many more options than is often assumed.
Mar 9 • 7 tweets • 2 min read
1/ Yes-- I've been meaning to literally do an entire talk on Simpson's Paradox because the concept is really quite simple.
Here's an example:
✅Hypothesis: higher body weight causes higher blood pressure.
💡If we only had scales and BP cuffs, we'd certainly see the relationship
2/ If you're just tuning in, I've done over 50 experiments with many of them hypercontrolled (like below) where I literally eat to an exact meal plan with exact timing, have nearly identical exercise, and try to sync sleep schedule as best as possible. cholesterolcode.com/the-oxldl-repl…
Feb 2 • 5 tweets • 2 min read
1/2 Example 1:
🚬 Imagine if the average person from the moment they're born were taught to be 2 pack a day smoker.
⛔️ Now imagine a fraction were born into families that were 0 pack a day smokers.
Would we expect that latter group to have greater longevity than the former?
2/2 Example 2:
Now imagine most people averaged 100 #LDL cholesterol over their lifetime.
But a fraction were born with a genetic mutation that kept their average at 20.
Would we expect that latter group to have greater longevity?
Feb 1 • 4 tweets • 2 min read
1/4 Interesting study regarding #LDL-C vs all cause mortality*
✅NHANES -- so it's #OpenScience 👏
✅Lowest LDL-C associates with highest ACM
⚠️ No short term censoring (more on this below)
Here are the observations I give my own family members based on what's I've learned in my N=1 experiments.
1) Nothing beats proximity.
The further I'm away from food, the less likely I am to eat it. Not just across town, but in the room.
2) Like many (but probably most), eating something outside my diet commitments on a holiday almost always results in my continually breaking that commitment from then on.
Some things I can "cheat" on (like "normal" pizza). Some I can't (like "normal" chocolate chip cookies).
Dec 19, 2022 • 4 tweets • 2 min read
Wow — i’m currently traveling for the holidays and tweeted this out before getting on the road (currently at a stop). I guess this is actually a topic with a lot of interest…
Yes, this was one of the things that got brought up. It’s actually where a lot of the arguing originated because naturally everyone wants to reassure everyone else not to feel insecure. But some chimed in that it isn’t “how the real world works”…
It focuses on #LMHRs, both in consideration of their high #LDL and an urgent call for expanded #research.
Why is this important?... /1 doi.org/10.1016/j.jacl…2/ Certainly the biggest impact is bringing this phenotype well into the spotlight.
If you've been following my work from the beginning, you can appreciate just how much energy I've put toward putting this phenotype in front of Lipidologists.
Dec 9, 2022 • 15 tweets • 7 min read
🧵 Dec 9th anniversary thread
On this day in 2015 I received a lab result that would alter the course of my life.
Just two weeks earlier I had gotten my very first bloodwork after half a year on #keto that showed my total and #LDL#Cholesterol had nearly doubled (!)… /12/ With that first test I was overcome with shock and curiosity — much more former than the latter.
I wanted to get a repeat test to confirm this wasn’t a lab error.
I wasn’t ready to give up #keto, but I was miserable enough that I ate considerably less.
Nov 29, 2022 • 9 tweets • 4 min read
1/ 🧵 I like a lot of @NutritionMadeS3's videos, but I'll concede this one was a little mixed, so I wanted to share some notes (it gets better by the end)
As always, I hope this will be received by everyone in a productive, respectful manner.