Prof. Shane Crotty Profile picture
Vaccines and immune system scientist. Professor, La Jolla Institute for Immunology (LJI), a non-profit research institute @ljiresearch. PhD not MD.

May 4, 2021, 6 tweets

Oral SARS-CoV-2
I love this paper! Important demonstration of SARS2 infection in the mouth. And outstanding paper on oral biology and immunology relevant for viral infections. I learned so much! 🧵

nature.com/articles/s4159…

Really important to understand the oral biology of SARS2 better. Including salivary glands!

Clear infection of multiple oral cell types, with cells of the salivary glands of particular note because of their production of saliva.

And complex immune cell infiltrates in the salivary glands of acute COVID-19 patients, as well as autopsies. Including T cells, B cells, and antigen presenting cells.

(I am catching up on my COVID reading)

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