This is concerning.
When controlling for age, body habitus, and other variables, people who had covid had sizes of key brain structures 4 standard deviations below average.
The hippocampal gyrus is responsible for memory, in part.
medrxiv.org/content/10.110…
These changes were not found to be different whether one was hospitalized or not.
The one metric where size increased post covid- ventricle volume- is a good marker for loss of brain matter. This usually increases with age.
And before people tell you this was unexpected- no. This was predictable. Furin cleavage sites confer neurotropism and this was my primary concern with the virus. With the knowledge it had a Sag, the situation appeared more dire. Downplayers are culpable.
I have been trying to convey this clear risk to people like Prasad and Munro who advocate to have kids in classrooms despite circulating neurotropic viruses with furin cleavage sites and superantigens.
Whether intentional or not, it seems to me all pathologically salient features of the virus like the Furin cleavage Site and SEB Superantigen were downplayed bc they went hand in hand with stoking the possibility of modifications a lá Gain of Function, whether true or not.
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