John Damianos, M.D. Profile picture
@MayoClinicGIHep Gastroenterology & Hepatology Fellow. Yale Internal Medicine, Dartmouth Med. 🦠Microbiome, brain-gut axis, diet, IBS, IBD, motility, #MedEd🇬🇷

Oct 24, 2021, 26 tweets

Early recognition of cirrhosis is important

We should CONFIRM the diagnosis, not assume it

Portal hypertension (i.e., HVPG) drives outcomes in cirrhosis

Life expectancy in compensated cirrhosis: 12 yrs
Decompensated: 3-4 years

Preventive care

⚠️Make sure they are vaccinated against COVID-19

Screening for esophageal varices

Pathophysiology of portal hypertension

Treatment of esophageal varices

Carvedilol might be the best

Outpatient management pearls

Ascites
✅Low sodium diet
✅furosemide and spironolactone

AKI in cirrhosis is usually pre-renal. Don't just assume it's HRS!

Hepatorenal syndrome: new and improved (see amazing article by @DougSimonetto in @bmj_latest!)

❓What to do with AKI in cirrhosis

Treatment of HRS

Keep you 👁 out for terlipressin!

Hyponatremia in cirrhosis

Hepatic encephalopathy

⚠️Keep broad differential
⚠️Measurement/following ammonia is NOT recommended

Spontaneous bacterial peritonitis (SBP)

💎s of the inpatient management of cirrhosis

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