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John Damianos, M.D. Profile picture
John Damianos, M.D.
@john_damianosMD
@MayoClinicGIHep Gastroenterology & Hepatology Fellow. Yale Internal Medicine, Dartmouth Med. 🦠Microbiome, brain-gut axis, diet, IBS, IBD, motility, #MedEd🇬🇷
Imanol S · Nutricionista Profile picture Ashok D Profile picture 2 subscribed
Mar 14 • 20 tweets • 8 min read
A master class on prokinetics from @NGMJournal! Here is a summary! 🧵👇

⚡️🎈〽️🪠🫀💩🚄🧠✳️🗯️💊📰🚽🔌🧪💡🧲📊🔎

#MedTwitter #GITwitter #motility #pharmacology

onlinelibrary.wiley.com/doi/full/10.11…
Image Pyridostigmine & neostigmine
⚡️cholinesterase inhibitors
🧠pyrido should not cross the blood-brain barrier
🚽evidence in chronic idiopathic constipation and acute colonic pseudo-obstruction
🫄pregnancy class C; excreted in breastmilk
🫀cholinergic side effects, esp bradycardia Image
Dec 15, 2022 • 20 tweets • 13 min read
I gave a talk on inpatient bowel regimens today for the @YaleMed @YaleIMed residents and students, with additional 💎s on outpatient #constipation. Here are the slides!

💩 💩 💩

#MedTwitter #GITwitter #motility #MedEd @YaleIM_Chiefs @MayoClinicGIHep Most inpatients require a bowel regimen. Our patients typically have most of the risk factors for #constipation!
Dec 13, 2022 • 15 tweets • 6 min read
Diet, gas, and the #microbiome 💨

#MedTwitter #GITwitter #diet #nutrition #IBS #SIBO

sciencedirect.com/science/articl… 💨The gut microbiota generates ~0.2L–1.5L of gas per day
💨>99%: hydrogen (H2), carbon dioxide (CO2), & methane (CH4)– *odorless*
💨foul smell of gas from <1%: sulfur–containing gases hydrogen sulfide (H2S), methanethiol (CH3SH), dimethyl sulfide [(CH3)2S] + volatile compounds
Oct 23, 2022 • 8 tweets • 6 min read
Summarizing our learning at #ACG2022 today! 🧑‍🎓

@tinahamd @AmCollegeGastro #MedTwitter #GITwitter 💎 GI bleeding🩸
Oct 23, 2022 • 17 tweets • 5 min read
Management of benign anorectal disorders with #AdilBharucha

#MedTwitter #GITwitter #ACG2022 Image 🔑Have patient complete symptom questionnaire to get a more detailed picture of their symptoms Image
Oct 23, 2022 • 20 tweets • 9 min read
Chronic #constipation with @umfoodoc

#MedTwitter #GITwitter #motility #ACG2022 Chronic constipation is common and has tremendous impact on quality of life
Oct 23, 2022 • 22 tweets • 9 min read
#Gastroparesis updates with @LindaNguyenMD

#MedTwitter #GITwitter #motility #ACG2022 Updated @AmCollegeGastro #gastroparesis guidelines
Oct 23, 2022 • 15 tweets • 8 min read
#Celiac disease mimics with @AmyOxentenkoMD

#MedTwitter #GITwitter #ACG2022 Do NOT prescribe a gluten-free diet unless we are positive this is #celiac disease!
Oct 23, 2022 • 19 tweets • 9 min read
#Celiac disease with #CarolSemrad

#MedTwitter #GITwitter #ACG2022 Defining #celiac disease and non-celiac gluten (more accurately, wheat) sensitivity
Oct 23, 2022 • 11 tweets • 6 min read
Enteric infections and food borne illness

#MedTwitter #GITwitter #IDTwitter #ACG2022 Image Amebiasis Image
Oct 23, 2022 • 15 tweets • 10 min read
Health maintenance in inflammatory bowel disease with @dr_fcalderaibd

#MedTwitter #GITwitter #IBD #ACG2022 Image Risk of serious and opportunistic infections with #IBD therapies Image
Oct 23, 2022 • 22 tweets • 9 min read
The role of #surgery in inflammatory bowel disease with
@IBDBen

#MedTwitter #GITwitter #IBD #ACG2022 Good medical therapy has reduced need for surgery, but many still will require surgery
Oct 23, 2022 • 19 tweets • 9 min read
Discussing inflammatory bowel disease treatments with patients, with @tinahamd

#MedTwitter #GITwitter #IBD #ACG2022 First, need to explain #IBD itself to patients
Oct 23, 2022 • 10 tweets • 7 min read
Endoscopic features of inflammatory bowel disease with @IBD_Afzali 🔦 🔥

#MedTwitter #GITwitter #IBD #ACG2022 Image Who's seen this? 😱 🙋‍♂️ Image
Oct 23, 2022 • 15 tweets • 8 min read
🎯 Goals in management of inflammatory bowel disease with @MLongMD

#MedTwitter #GITwitter #IBD #ACG2022 Only a minority of Crohn disease patients have an indolent course. The majority have PROGRESSIVE disease. We need to identify these patients and treat them in the window of opportunity.
Oct 23, 2022 • 17 tweets • 8 min read
Disorders of the hepatic and mesenteric
circulation

#MedTwitter #LiverTwitter #GITwitter #Liver #ACG2022 ⚠️Remember your anatomy!
Oct 23, 2022 • 10 tweets • 5 min read
Acute LOWER GI bleeding 🩸

#MedTwitter #GITwitter #ACG2022 ⚠️Black >>> white for diverticular bleeding and rates are 📈
Oct 23, 2022 • 16 tweets • 10 min read
UPPER GI bleeding 🩸 with @YaleDigestive #LorenLaine

#MedTwitter #GITwitter #ACG2022 🔦 Risk stratification
Oct 23, 2022 • 11 tweets • 6 min read
Anticoagulants and antiplatelets during GI bleed🩸with the 👸 of #CardioGI herself, @NeenaSAbrahamMD!

#MedTwitter #GITwitter #ACG2022 #hematology #hemetwitter Regardless of cardiovascular indication for AC/AP, GIB risk ⬆️ with AGE
Oct 23, 2022 • 26 tweets • 15 min read
Microbiota-based therapeutics in the treatment of recurrent Clostridioides difficile 🦠

@DrPaulGastro @Khanna_S @caterina_oneto

#MedTwitter #GITwitter #IDTwitter #ACG2022 #Cdiff Pathogenesis of CDI
1. Disruption of #microbiome (antibiotics) ▶️ loss of colonization resistance
2. Colonization
3. Spore ▶️ vegetative ▶️ toxin
4. Recurrence cycle or restoration of microbiota
Aug 12, 2022 • 63 tweets • 12 min read
⭐️Everything you need to know about H. pylori: the Maastricht V/Florence Consensus Report summarized❗️ 🧵

🦠🦠🦠🦠🦠🦠🦠🦠🦠🦠🦠🦠

#MedTwitter #GITwitter #IDTwitter #microbiome

gut.bmj.com/content/71/9/1… INDICATIONS/ASSOCIATIONS
🦠HP gastritis is an infectious disease irrespective of symptoms/complications

⚠️HP▶️chronic active gastritis in ALL colonized individuals. This can▶️peptic ulcer disease, atrophic gastritis, gastric adenocarcinoma, MALT. Eradication prevents all of this