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Dr. Doug Corrigan Profile picture
Dr. Doug Corrigan
@ScienceWDrDoug
Ph.D. Biochemist & Molecular Biologist, Physicist, Award Winning Global Super Solver, Materials Scientist, Innovator, Space Enthusiast

Nov 13, 2021, 6 tweets

1/ Plan taken directly from their investor relation docs…

2/ Testing new Spike Protein Sequence Based on Escape Variants

3/ Epitope Mapping in NTD and RBD Domains of Spike Protein with Potential for Vaccine Escape

4/ 7 Mutations in Spike Protein cause almost 100 fold drop in observed antibody neutralizing titer compared to original WT sequence (which current vaccine is designed around)

5/ Methodology to predict next variant with escape potential.

Taken from —> investors.modernatx.com/static-files/c…

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