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Medicine Podcast || Inspiring curiosity & critical thinking || 5 Pearls || Mind the Gap || Hoofbeats || At the Bedside || Gray Matters || Biweekly Wed.

Jan 5, 2022, 7 tweets

1/ 🚨New Episode! 🚨

What is an “appropriate” Hgb bump?

Why do we usually say 1g/dL for 1 pRBC?

iTunes: bit.ly/coreimpodcast
Show Notes: bit.ly/3eUgyGw

First, let’s figure out how many grams of hemoglobin are donated?

2/ What is the patient’s PRE-transfusion #intravascular volume?

Usually 6.5% of body weight for women 👩
Usually 7.5% of body weight for men👨

3/ What is the patient’s POST-transfusion intravascular volume?

4/ What rise in hemoglobin can be expected after transfusion?

It's all division here to get the g per dL bump you expect and viola!

It works out nicely for a 13g/dL donor Hgb to a 70Kg male recipient !

5/ While the 1g/dL bump for 1 unit pRBC is a good rule of thumb, there are other factors that can affect hgb response to transfusion!

6/ Let’s apply two different scenarios with different:
(1) amount of g/dL of donor and
(2) body weight of the recipient

Takeaway: 1 unit pRBC can increase hgB response anywhere from 0.6g/dL to ~1.6g/dL!

7/ Thanks for following along, #MedTwitter!

And a huge thank you to our team:
Hosts: @FreedoBaggins, @ShreyaTrivediMD
Peer Review: Bentley Rodrigue, MD
Graphic: @Preeyal_P
Audio Editor: @onlysolon

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