Carl Fuller et al are at it again.
This is wild. 16,384 CMOS chip capable of single molecule movies at each pixel.
Each pixel has a protein nanowire bridging it. These are assembled with electrophoresis.
Once wired, click chemistry binds one molecule.
pnas.org/content/pnas/1…
20nM gap for the nanowire peptide bridge.
1000Hz read outs. 0-400pAmp sensors.
Chip features
Simple Oligo binding assays are information rich.
The diversity of applications is impressive.
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