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The Allen Institute is committed to solving mysteries of bioscience — researching the unknown of human biology, in the brain, the cell and the immune system.

Feb 9, 2022, 13 tweets

Announcing 23 Allen Distinguished Investigator awards —representing $15.5M in total funding— aiming to advance #FrontierScience in: neural circuits of under-studied organisms, advances in mammalian synthetic biology & micropeptides involved in immunity 🧵1
alleninstitute.org/what-we-do/fro…

Allen Distinguished Investigator Robyn Crook @SFStateBIO is leading a project to study the neural control of movement in cephalopods, animals that have the most complicated nervous systems of the invertebrate world. #FrontierScience 🐙
alleninstitute.org/what-we-do/fro… 🧵 2

How does a new kind of behavior arises in evolution? Allen Distinguished Investigators @neuroluci, & @SGRodriques at @TheCrick are studying larvae brains of a species of fruit fly that have evolved to jump 10 times their body length. #FrontierScience alleninstitute.org/what-we-do/fro… 🧵 3

Where did modern nervous systems come from? Allen Distinguished Investigators Joseph Ryan, Mark Martindale, and @StrotherLab, are leading a project at @Whitney_Lab to better understand the nervous systems of ctenophores. #FrontierScience alleninstitute.org/what-we-do/fro… 🧵4

The human microbiome is inextricably interwoven with our health. Allen Distinguished Investigators Ami Bhatt, Michael Bassik & @LivnatJerby are leading #FrontierScience at @StanfordDeptMed to look at the role of the gut microbiome’s micropeptides. alleninstitute.org/what-we-do/fro… 🧵5

Allen Distinguished Investigators @SlavoffL, Grace Chen, and Joseph Craft are leading a project at @YaleChem to explore the roots of the devastating autoimmune disease #lupus. #FrontierScience | alleninstitute.org/what-we-do/fro… 🧵6

Allen Distinguished Investigators @lizzyzhao & @scimaven, will lead a project at @RockefellerUniv and CUNY @Hunter_College to better understand how immune genes that code for tiny proteins known as #micropeptides arise in evolution. #FrontierScience alleninstitute.org/what-we-do/fro… 🧵7

To yield more information about human health & disease, Allen Distinguished Investigator @Pulin_Li at @WhiteheadInst is leading a project to improve the development of organoids, lab-grown mini-organs grown from human stem cells. 🧫 #FrontierScience: alleninstitute.org/what-we-do/fro… 🧵8

Currently, brain organoids are missing several key attributes of the real thing. Allen Distinguished Investigator @AdrianRanga1 is leading #FrontierScience at @KU_Leuven to apply the emerging field of “soft robotics” to brain organoids. 🧠 🤖 alleninstitute.org/what-we-do/fro… 🧵9

Better understanding how human livers develop could allow researchers to grow new organs in the lab. Learn about Allen Distinguished Investigator @kellystevenslab's #FrontierScience on: Mid-terminal human synthetic liver organogenesis at @UWMedicine
alleninstitute.org/what-we-do/fro…
🧵10

Allen Distinguished Investigators Wilson Wong, @ChrisChenMD, and @Kottond, are leading #FrontierScience at @BU_Tweets to test a classic but unproven theory about how our lungs develop their complicated branching structures. alleninstitute.org/what-we-do/fro… 🧵11

Allen Distinguished Investigators @nzmyachie, @nika_shakiba, and @penningerlab, are leading #FrontierScience at @UBC to trace the “family trees” of individual stem cells as they grow and divide into organoids, lab-grown mini-organs.alleninstitute.org/what-we-do/fro… 🧵12

In related news ⭐️ We are seeking Letters of Intent for #FrontierScience funding to support technology development in Protein Lifespan and Nutrient Sensing. Up to eight awards will be made for up to $10M total funding. Apply by March 1: alleninstitute.org/2022-adi-open-…

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