@TropicalVertic1 @fitterhappierAJ Wrt your question in yesterday's discusion. Long answer
- IMO, anti-viral nasal spray & mouthwash/gargle are the most significant underused personal tools for minimizing risk of airborne transmission – next to an effective face mask (high filtration, good seal, properly worn)...
@TropicalVertic1 @fitterhappierAJ - We control what we put on/in our body (eg, face mask, nasal spray, mouthwash, sealed eyewear, handsanitizer/gloves, supplements) while we are inside indoor spaces even with poor air quality we do not control (e.g., CO2 monitor, ventilation, air purification, air disinfection).
@TropicalVertic1 @fitterhappierAJ - Nasal spray & mouth wash may help prevent transmission of the SARS2 virus (even more when they backup an effective mask) & eliminate the virus (particularly in early treatment) in the nasal cavity, throat & mouth. Virus uses these ACE2-rich areas of the upper respiratory tract
@TropicalVertic1 @fitterhappierAJ as incubators (factories) & entry channels into body. Thus our ACE-2 rich nose, throat & mouth must be effectively protected from infection. Even an N99 mask may occasionally fail & there are situations when a person removes the mask (eg, eating, presenting)
@TropicalVertic1 @fitterhappierAJ Studies have been done or are ongoing on various nasal spray & mouthwash products. Many studies are impacted by lack of resources (funding, efficiency, time to complete) & regulatory redtape. They are less sexy & profitable products (e.g., vs vaccines) – despite their benefits.
@TropicalVertic1 @fitterhappierAJ - Anti-viral nasal spray with iota-carrageenan, nitric oxide, heparin, hypochlorous acid, povidone iodine, etc
holisticprimarycare.net/topics/infecti…
ncbi.nlm.nih.gov/pmc/articles/P…
abc.net.au/news/2021-12-2…
birminghambiotech.co.uk/anti-viral-nas…
carragelose.com/en/portfolio/l…
fau.eu/2021/04/22/new…
@TropicalVertic1 @fitterhappierAJ healtheuropa.com/broadening-the…
sciencedirect.com/science/articl…
ichgcp.net/de/clinical-tr…
clinicaltrials.gov/ct2/show/NCT04…
clinicaltrials.gov/ct2/show/NCT04…
ncbi.nlm.nih.gov/pmc/articles/P…
mdpi.com/1422-0067/22/2…
frontiersin.org/articles/10.33…
nytimes.com/interactive/20…
ncbi.nlm.nih.gov/pmc/articles/P…
@TropicalVertic1 @fitterhappierAJ banglajol.info/index.php/BRC/…
immunemist.com/products/immun…
- A nasal spray is only as good as how well it is applied into the nose (to properly cover the nasal cavity). Trajectory & head/bottle positions in these videos:
@TropicalVertic1 @fitterhappierAJ - Anti-viral mouth wash: Gargle throat & mouth with an anti-viral mouthwash containing cetylpyridinium chloride (eg, Colgate Total Pro-Shield mouthwash)
straitstimes.com/singapore/heal…
channelnewsasia.com/singapore/thro…
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