@TumorBoardTues 1/13 #TumorBoardTuesday #ProstateCancer #OncTwitter
👉55 yo♂️dxed with localized prostate Ca
⬆️Elevated PSA🟰8.0 ng/mL
🩺Abnormal DRE w/ T2 disease
👨👩👧👦Family Hx
👩🦳Mother w/ ovarian Ca
👨🦳Paternal uncle w/ prostate Ca
👨🦳Father w/ heart dz
➡️Two brothers - no cancer
@TumorBoardTues Would you order germline testing for this patient?
@TumorBoardTues #TumorBoardTuesday
🔪Underwent radical prostatectomy
🔬pT3a with extracapsular extension, confirmed Gleason 4+5=9
➡️Post-operative PSA is undetectable then starts to rise
☢️Salvage radiation therapy with 6 months of CAB initiated
@TumorBoardTues Would you order germline testing now?
@TumorBoardTues #TumorBoardTuesday
2 years later, PSA⬆️again
🖥️CT CAP imaging and bone scan⛔️for metastases
💉ADT resumed
@TumorBoardTues 1 year later, PSA⬆️on ADT
✅Bone mets on bone scan and CT
👉PSA 18.0 ng/mL
✅Good ECOG PS with controlled pain
Now what would you do?
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