Had a pt 36 yr old with 8 wks pregnancy come in today with seizures and metabolic Acidosis. There was a h/o oral consumption of 30 ml of #eucalyptus oil.
There was no kidney dysfunction. I was called for Rx of Acidosis. I have not seen eucalyptus oil poisoning before.
In adults, death is commonly seen after ingestion of 30 ml, but can be encountered after 4-5 ml also.
ncbi.nlm.nih.gov/pmc/articles/P…
In children, a dose of 2-3 mL can induce mild CNS depression with drowsiness and/or dizziness and ataxia. A dose of ≥5 mL can induce significant CNS depression with coma.
Eucalyptus oil inhalation can also induce seizures. A study from #Bangalore from @apollohospital @SakraHospital & St Johns Medical College Hospital report 10 cases of EO inhalation–induced seizures, 8 patients had GTCS and two had CPS. onlinelibrary.wiley.com/doi/full/10.10…
Essential oils of 11 plants are powerful convulsants (eucalyptus, fennel, hyssop, pennyroyal, rosemary, sage, savin, tansy, thuja, turpentine & wormwood) due to highly reactive monoterpene ketones - camphor, pinocamphone, thujone, cineole, pulegone, sabinylacetate & fenchone.
Pt remains drowsy but arousable. No further seizures. After iv bicarb infusion, the ABG...
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