Thread by @zalaly

📣 New from my team in @TheLancetInfDis

Long-term outcomes of people hospitalized for COVID-19 vs seasonal influenza

A 🧵

thelancet.com/journals/lanin…

The study included:

81,280 individuals hospitalized for SARS-CoV-2
&
10,985 individuals hospitalized for seasonal influenza

We followed them for 1.5 years to characterize the risks of death, health care utilization & 94 health outcomes

thelancet.com/journals/lanin…

Covid had higher risk of death, healthcare utilization and sequelae in most organ systems than flu

This was evident in pre-delta, delta, and omicron; and also evident in vaccinated and unvaccinated individuals.

thelancet.com/journals/lanin…

Risks were higher in Covid for all organ systems except for the pulmonary system which was higher in flu

Covid is more multisystemic than flu
Flu is more respiratory than Covid

thelancet.com/journals/lanin…

COVID-19 had a comparatively higher burden of health loss than seasonal influenza in both the acute and post-acute phase

thelancet.com/journals/lanin…

Both COVID-19 and seasonal influenza had a higher burden of health loss in the post-acute phase of infection compared to their respective acute phases
thelancet.com/journals/lanin…

Conceptualizing these illnesses (as we often do) as acute events eclipses the much larger burden of health loss that occurs in the post-acute phase.

thelancet.com/journals/lanin…

Thanks to the amazing @sourwine for developing this press release (link below).



A clear accounting of the findings.

@WUSTLnews
@WUSTLmedmedicine.wustl.edu/news/long-flu-…

Enormously grateful to the patient community & advocacy groups

Thanks also to our reviewers, editors, and all who supported us in this project

And to my wonderful co-authors @Biostayan and Taeyoung Choi

@WUSTL
@WUSTLmed
@VREFSTL
@VAResearch
@vahsrd

thelancet.com/journals/lanin…