"After centuries of pestilence and decades of global vaccination, MEASLES VIRUS (MeV) genotypes CAPABLE of EVADING VACCINE-INDUCED IMMUNITY HAVE NOT EMERGED"
IS IT SURE ?
2) If we strongly recommend vaccination for measles, the question of whether the measles virus (MeV) has mutated, and requires a change of vaccine, nevertheless seems important for us.
3) First there was a thread from our friend @jukka235 with the example of several countries including, for example, Austria. A Country with a high level of measles vaccinations, which has not stopped vaccinating during the pandemic and is experiencing a strong outbreak
4) Then there was this Eurosurveillance letter on a virus mutation discovered in Italy.
eurosurveillance.org/content/10.280…
5) Certainly the substitution rate of MeV (left) is in no way comparable to that of SARS-COV-2 (right)
6) However, several studies have addressed the subject of MeV mutations.
"Measles Encephalitis: Towards New Therapeutics"
researchgate.net/publication/33…
7) "Serotypic evolution of measles virus is constrained by multiple co-dominant B cell epitopes on its surface glycoproteins"
sciencedirect.com/science/articl…
8) "Collective Measles Virus Mutations Linked to Fatal Encephalitis"
genengnews.com/news/collectiv…
9) "Mutations in the Fusion Protein of Measles Virus That Confer Resistance to the Membrane Fusion Inhibitors"
ncbi.nlm.nih.gov/pmc/articles/P…
10) and to end, an interesting article :
"Study reveals how measles virus mutates and spreads in the human brain"
news-medical.net/news/20231221/…
11) If the hypothesis of the re-emergence of measles following the weakening of the immune system linked to multiple reinfections with SARS-COV-2, possible mutations of MeV remains in our opinion, a plausible hypothesis, to be followed.
Thanks for reading 🙏
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