Daniel Brittain Dugger Profile picture
#LongCovid Advocate. Bail Bond Software Solutions. When It Hits The Fan Bail Bonds.

Jun 14, 20 tweets

I'll never forget the betrayal of my family members and take comfort in knowing you losers fucked yourselves and won't be here long, LMAO.

Go on, lie to those kids some more.

See? It's always been an unscientific narrative and it always will be.
2021 Jan 7
Evidence of Pulmonary Hypertension after SARS-CoV-2 Infection in Subjects without Previous Significant Cardiovascular Pathology
pmc.ncbi.nlm.nih.gov/articles/PMC78…

March of 2021, we learned of increased TGF-b signaling.
Published: 30 March 2021
SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself
nature.com/articles/s4146…

November of 2021, the very protein that contributes to PAH and COPD in the HIV+ appeared at citation #20.
Published: 15 November 2021
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis
nature.com/articles/s4146…

"20. Schwartz, O., Maréchal, V., Le Gall, S., Lemonnier, F. & Heard, J. M. Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein. Nat. Med 2, 338–342 (1996)."

2023 Apr 10
Enhanced inhibition of MHC-I expression by SARS-CoV-2 Omicron subvariants
Akiko Iwasaki
pmc.ncbi.nlm.nih.gov/articles/PMC10…

She told everyone and they still decided to FUCK the kids, HILARIOUS!
"We also included HIV Nef as a positive control for downregulating both MHC-I and MHC-II (30, 31), and SARS-CoV ORF8a/b proteins as a negative control."

She also observed Protein E operate mechanistically as HIV's Tat which contributes to increased TGF-b signaling and CFTR silencing (not observed in ME/CFS).

"We found that in addition to ORF8, SARS-CoV-2 E, M, and ORF7a substantially down-regulated MHC-I within the cells expressing these viral proteins."

March 26, 2024
SARS-CoV-2 targets ribosomal RNA biogenesis
cell.com/cell-reports/f…

"Finally, the Tat protein of human immunodeficiency virus interacts with FBL and U3 snoRNA, impairing pre-rRNA processing and depleting mature ribosomes."

Long COVID Is Fueling a Mental Health Crisis in Children
unmc.edu/healthsecurity…

"These children reported a quality of life comparable to peers with serious illnesses like cancer or cystic fibrosis, with many expressing a deep sense of ineffectiveness and loss of confidence."

Might as well lie to children to more, not like they'll remember anything with their blob brains.
Published: 23 July 2024
Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 spike protein
nature.com/articles/s4159…

Could have saved them, chose not to. Is that not the legacy of many?
HIV Tat Protein Induces the TGF-β Signaling Pathway and Suppresses the CFTR Biogenesis and Activity by microRNA-Regulated Gene-Silencing Mechanism
faseb.onlinelibrary.wiley.com/doi/abs/10.109…

Could have saved them, were too MEntally ill and weak to do so.
Pathogenesis of HIV-Associated Pulmonary Hypertension
Potential Role of HIV-1 nef
pmc.ncbi.nlm.nih.gov/articles/PMC31…

"The HIV-PH mechanism remains unknown, but HIV proteins such as Tat and Nef may play a role. HIV-1 Nef is a broad-spectrum adaptor protein that may affect HIV-infected and uninfected pulmonary vascular cells."

Could have saved them, chose not.
HIV and Chronic Obstructive Pulmonary Disease
Is It Worse and Why?
pmc.ncbi.nlm.nih.gov/articles/PMC31…

"IV-infected persons might have increased susceptibility to apoptosis because the HIV proteins Tat and Nef may induce endothelial cell apoptosis."

Johnny, your mother should have named you Whitney, LMAO!

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