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Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
@edgarvlermamd
May 24, 2019 β€’ 18 tweets β€’ 26 min read β€’ Read on X
Scrolly
Hey #Nephpearls followers‼️ Learn more about monoclonal gammopathies by following the tweets of @onconeph
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
πŸ‘‰πŸΌ fourwaves-sots.s3.amazonaws.com/static/media/u… Image
MT @onconeph Categorization of MGRS-associated renal lesions ca. 2019 from @NatRevNeph
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ nature.com/articles/s4158… ImageImage
MT @onconeph Diagram of MGRS-associated renal lesions ca. 2015 from @Kidney_Int
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ kidney-international.org/article/S0085-… ImageImage
MT @onconeph Patterns of nephron injury associated with paraproteins ca. 2016 from @CJASN
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ cjasn.asnjournals.org/content/clinja… ImageImage
MT @onconeph Overview of novel immunotherapeutic approaches in multiple myeloma ca. 2016
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ clincancerres.aacrjournals.org/content/clinca… ImageImage
MT @onconeph Mechanism of action of CD38 antibodies ca. 2018
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ bloodjournal.org/content/bloodj… ImageImage
MT @onconeph Multimodality targeting of multiple myeloma in the context of the BM microenvironment ca. 2015
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ bloodjournal.org/content/bloodj… ImageImage
MT @onconeph Bench-to-bedside translation of novel agents in myeloma ca. 2016
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ bloodjournal.org/content/bloodj… ImageImage
MT @onconeph VARGA: Proposed algorithm for CKD and MGUS diagnosis
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls Image
MT @onconeph Treatment algorithm for newly diagnosed AL Amyloidosis
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ msmart.org/treatment-guid… Image
MT @onconeph Monoclonal antibodies in myeloma ca. 2015
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ nature.com/articles/leu20… ImageImage
MT @onconeph AL Amyloidosis: New hematologic and cardiac response and progression criteria ca. 2012
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ ascopubs.org/doi/pdfdirect/… ImageImageImage
MT @onconeph Amyloidosis is a difficult diagnosis‼️
πŸ“Œ Can involve any organ/ organ system in any combination
πŸ“Œ Presents with β€œcommon” symptoms
πŸ“Œ There is NO single blood test for amyloidosis
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ ncbi.nlm.nih.gov/pmc/articles/P… ImageImage
MT @onconeph Amount of amyloid deposition determines outcomes
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ ahajournals.org/doi/pdf/10.116… ImageImage
MT @onconeph Amyloidosis: Late diagnosis remains a problem‼️
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ bloodjournal.org/content/bloodj… ImageImage
MT @onconeph Timeline of treatments for AL Amyloidosis ca. 2019
#IKMG2019 πŸ‡¨πŸ‡¦
#Onconephrology πŸ¦€
#Nephpearls
πŸ‘‰πŸΌ karger.com/Article/Pdf/49… ImageImage
Algorithm for renal biopsy evaluation in patients suspected to have MGRS ca. 2019
#Onconephrology πŸ¦€ #Nephpearls
πŸ‘‰πŸΌ nature.com/articles/s4158… ImageImageImage
Dysproteinemia and the Kidney: Core Curriculum ca. 2019 from @AJKDonline

Differentiating -
πŸ”¬LC Cast Nephropathy
πŸ”¬LC (AL) Amyloidosis
πŸ”¬LC Deposition Disease
πŸ”¬LC Proximal Tubulopathy

#Nephpearls

πŸ‘‰πŸΌ ajkd.org/action/showPdf… ImageImage

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More from @edgarvlermamd

Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Feb 26, 2022
Advancing Evidence-Based Care in Diabetes and CKD
#ISNWCN πŸ‡²πŸ‡Ύ #Nephpearls

πŸ‘‰ kdigo.org/wp-content/upl…
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Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Feb 26, 2022
.@goKDIGO Glomerular Diseases Guideline: Reflections on a Decade of Progress with @adrianliew8 @ReichHeather @Dr_KeishaGibson
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πŸ‘‰ kdigo.org/wp-content/upl…
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@goKDIGO suggest using the "prediction tool" that was derived from the largest & most geographically diverse cohort to date

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IgA Nephropathy: The @goKDIGO treatment algorithm recommends consideration of use of corticosteroids in patients with "persistent proteinuria >1g/day" if the risk/benefit profile is favorable

πŸ“Œ A GFR of 30 is considered a threshold for treatment

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Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Feb 23, 2022
First clinical-grade porcine πŸ– kidney xenotransplant using a human decedent model ca. 2022 from @amjtransplant #NephJC #Nephpearls

#VisualAbstract by @NamrataYParikh

πŸ‘‰πŸΌ pubmed.ncbi.nlm.nih.gov/35049121/ Image
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kidney360.asnjournals.org/content/1/7/657 ImageImage
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Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Jan 30, 2022
Nephrolithiasis 101: When to order a 24-hour urine collection #Nephpearls

Multiple or metabolically active stones (stones that increase in size/ number w/in a year)

Children

Demographic groups not typically prone to stone formation

Stones other than those containing calcium ImageImage
Interpretation of urine chemistries to identify lithogenic risk factors and assess the contribution of diet to the formation of kidney stones ca. 2016 from @ravineja #Nephpearls

sciencedirect.com/science/articl… Image
Neglected analytes in the 24 hour urine: ammonium and sulfate ca. 2021 from @CO_Neph_Hype @ravineja #Nephpearls

πŸ‘‰ pubmed.ncbi.nlm.nih.gov/34798636/ ImageImageImageImage
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Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Jan 26, 2022
PREDNOS 2: Evaluation of Daily Low-Dose Prednisolone During URTI to Prevent Relapse in Children w/ Relapsing Steroid-Sensitive Nephrotic Syndrome ca, 2022 from @JAMAPediatrics #NephJC #IPNAJC #Nephpearls

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Low-dose versus conventional-dose prednisolone for nephrotic syndrome relapses: a randomized controlled non-inferiority trial ca. 2022 from @Ped_Neph #NephJC #IPNAJC #Nephpearls

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link.springer.com/article/10.100…
PREDNOS: Sixteen-week versus standard eight-week prednisolone therapy for childhood nephrotic syndrome ca. 2019 from @bmj_latest #NephJC #IPNAJC #Nephpearls

#VisualAbstract by @jbda19

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Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Nov 17, 2021
Clinical Practice Guideline for the Management of Glomerular Diseases ca. 2021 from @goKDIGO #NephJC #Nephpearls
#VisualGraphics by @michaelturk6

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πŸ‘‰ global.oup.com/academic/produ…
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πŸ‘‰ pubmed.ncbi.nlm.nih.gov/34556256/
Read 4 tweets

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