Neointimal hyperplasia
📌 Higher risk in AVG
📌 Usually in the venous segment downstream from the graft-vein anastomosis
👉🏼 Poor flow in the graft
👉🏼 Prolonged bleeding after removal of needles (⬆️ Intragraft pressure)
👉🏼 Leads to graft thrombosis #Nephpearls#DialysisDirector
AVF maturation: Rule of 6
📌 Assess for signs of maturation at 4-6 weeks
📌 Vein diameter at least 6 mm (at time of intended use)
📌 < 6 mm below the skin
📌 BFR of at least 600 mL/min
📌 Straight segment for cannulation at least 6 cm in length #Nephpearls#DialysisDirector
AVG maturation: A PTFE graft should not be cannulated for at least 2 weeks after placement
It is considered mature when -
📌 Edema and erythema have resolved
📌 AVG course is easily palpable #Nephpearls#DialysisDirector
Most common sites of AVF/ AVG stenosis:
📌 AVF: juxta-anastomotic region
📌 AVG: at or just distal to the graft–vein anastomosis #Nephpearls#DialysisDirector
IgA Nephropathy: The @goKDIGO treatment algorithm recommends consideration of use of corticosteroids in patients with "persistent proteinuria >1g/day" if the risk/benefit profile is favorable
📌 A GFR of 30 is considered a threshold for treatment
Nephrolithiasis 101: When to order a 24-hour urine collection #Nephpearls
Multiple or metabolically active stones (stones that increase in size/ number w/in a year)
Children
Demographic groups not typically prone to stone formation
Stones other than those containing calcium
Interpretation of urine chemistries to identify lithogenic risk factors and assess the contribution of diet to the formation of kidney stones ca. 2016 from @ravineja#Nephpearls
PREDNOS 2: Evaluation of Daily Low-Dose Prednisolone During URTI to Prevent Relapse in Children w/ Relapsing Steroid-Sensitive Nephrotic Syndrome ca, 2022 from @JAMAPediatrics#NephJC#IPNAJC#Nephpearls
Low-dose versus conventional-dose prednisolone for nephrotic syndrome relapses: a randomized controlled non-inferiority trial ca. 2022 from @Ped_Neph#NephJC#IPNAJC#Nephpearls
PREDNOS: Sixteen-week versus standard eight-week prednisolone therapy for childhood nephrotic syndrome ca. 2019 from @bmj_latest#NephJC#IPNAJC#Nephpearls