CVVHD
π Dialysate is passed through the dialysate compartment of the filter continuously and at a slow rate
π Diffusion is the primary method of solute removal
π Fluid removal: Usually about 3β6 L per day #Nephpearls#DialysisDirector
CVVH
π Dialysate is not used
ππΌ Large volume (~ 25β50 L/day) of replacement fluid is infused into either inflow or outflow blood line
π Convection is the primary method of solute removal
π Fluid removed = Replacement fluid + excess fluid removed #Nephpearls#DialysisDirector
CVVHDF
π Dialysate is used
ππΌ Replacement fluid is infused into either inflow or outflow blood line.
π Diffusion and Convection are the methods of solute removal
π Fluid removed = Infused Fluid + Net Volume removed #Nephpearls#DialysisDirector
SCUF
π Set-up is similar to that for CVVHD and CVVHDF
π Neither dialysate nor replacement fluid is used
π Minimal solute removal via convection
π Fluid removal: Usually about 3β6 L per day (similar to CVVHD) #Nephpearls#DialysisDirector
SLED
π Form of intermittent hemodialysis
π Extended (6-10 hours) session length
π β¬οΈ BFR (200 mL/min)
π β¬οΈ DFR (100-300 mL/min)
π Diffusion is the primary method of solute removal #Nephpearls#DialysisDirector
IgA Nephropathy: The @goKDIGO treatment algorithm recommends consideration of use of corticosteroids in patients with "persistent proteinuria >1g/day" if the risk/benefit profile is favorable
π A GFR of 30 is considered a threshold for treatment
Nephrolithiasis 101: When to order a 24-hour urine collection #Nephpearls
Multiple or metabolically active stones (stones that increase in size/ number w/in a year)
Children
Demographic groups not typically prone to stone formation
Stones other than those containing calcium
Interpretation of urine chemistries to identify lithogenic risk factors and assess the contribution of diet to the formation of kidney stones ca. 2016 from @ravineja#Nephpearls
PREDNOS 2: Evaluation of Daily Low-Dose Prednisolone During URTI to Prevent Relapse in Children w/ Relapsing Steroid-Sensitive Nephrotic Syndrome ca, 2022 from @JAMAPediatrics#NephJC#IPNAJC#Nephpearls
Low-dose versus conventional-dose prednisolone for nephrotic syndrome relapses: a randomized controlled non-inferiority trial ca. 2022 from @Ped_Neph#NephJC#IPNAJC#Nephpearls
PREDNOS: Sixteen-week versus standard eight-week prednisolone therapy for childhood nephrotic syndrome ca. 2019 from @bmj_latest#NephJC#IPNAJC#Nephpearls