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Laurence Badgley, M.D. Profile picture
@BadgleyLaurence
Aug 21, 2019 • 9 tweets • 2 min read • Read on X
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Hydromorphone (dilaudid) not interact with CYP-450 enzyme system, but rather metabolized by another pathway. Many patients w. EDS have defective CYP-450 metabolism, a genetic trait, so the active metabolites of other opiates are underproduced, resulting in ineffective analgesia. t.co/Hr0vn5P7GT
Dr. Tenant demonstrated many of the more widely promoted (by doctors) analgesics like hydrocodone (Norco) are metabolized by CYP-450 enzymes & in many people there are genetic defects (CYP-2D6, CYP-2C9, CYP-2C19) that ineffectively generate the active metabolite, w. ill results.
Doctors are mostly ignorant of these enzyme dynamics. When patients complain of ineffective analgesia, doctors assume the patient is “drug seeking”. Once branded, the patient commonly finds resistance vs. opiates from other doctors who review the medical record.
A problem in patients with pain generated in soft tissues is that blood tests & imaging studies do not reveal the pain generators, which are often inflamed entheses, loci where soft tissues (ligaments & tendons) attach to bone.
IMO, etiology of inflamed entheses is chronic biomechanical stress on soft tissues attempting to hold the body together & upright within the ambient gravitational field. Lose joints (injuries & inheritance) affect this ability. Weak muscles from sedentary inactivity are complicit
Cortisone & local injectable anesthetics can provide a few days or weeks of respite, but in #HSD patients there are frequently too many (myriad) inflamed loci to treat. This is where opiates become useful to allay pain so patients can rehabilitate.
Rehabilitation requires physical therapies to reduce (massage) muscle spasms, correct (exercise) crossed muscle syndromes, tonify (aqua therapy & walking) muscles of upright posture, and correct joint subluxations (Prolotherapy).
The general rehabilitation concept is to strengthen & stabilize the body tower. Efforts also need to be made to reduce body tower mass with a Paleolithic style ketogenic diet that is low carbohydrate high fat (LCHF).
CONCLUSIONS: Meat is good. Analgesics help rehabilitation efforts.

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More from @BadgleyLaurence

Laurence Badgley, M.D. Profile picture
Oct 26, 2025
Di-Sulphyl-Methyl-Oxymol is a natural biochemical extracted from tree wood being rendered to make paper. It is highly non-toxic to the human body and for more than 50 years has been injected into the veins of humans to unblock arteries beset with atherosclerosis.

DMSO is one of natures strongest free radicle scavengers. I once met a Neurosurgeon who kept a vial in his glove compartment with a note that if he had an accident and blood bleed into his brain this 50 cc was to be injected into his blood to prevent oxidation of his brain tissue by the iron in blood.
@AlexMadden41655 @MidwesternDoc @jimmy_dore DMSO is used by veterinarians to treat animals with inflamed joints. DMSO, when put in the skin immediately penetrates it. People who use Cannabis lotion pain killers dab DMSO onto the lotion to drive it down to the joints to take away pain.
@AlexMadden41655 @MidwesternDoc @jimmy_dore About 50 years ago, DMSO was featured by Dan Rathers on 60 minutes and as a wonder drug. Of course the dominant paradigm at that time was “better living through chemistry” ala Big PHARMA, so the idea was denigrated.
Read 7 tweets
Laurence Badgley, M.D. Profile picture
Jun 9, 2025
What Simone knows, if not scientifically then experientially, is that males can never accomplish the intensity of gymnastic skill as women. Women, 15%, are genetically endowed with hypermobile ligaments & connective tissues. They have delicate pelvises that expand. Tis a game changer. Men can never birth babies nor contort their musculoskeletal system so angularly in space.
@Yo_Retta @iAnonPatriot Males will never ever ascend to the skills that women inherently posses. Natural biology forbids it.
So Simone is elegarient, and safely so, as she offers a “democratic mind set”, and a cloaked way to skew gymnastic reality onto a level playing field. Smart posture to take if you already know, more than all “others”, that males are already defaulted and de facto chromosome losers in the gymnastic world.
Read 4 tweets
Laurence Badgley, M.D. Profile picture
Jun 3, 2025
ENERGY INSTRUCTION:
The frieze depicts Sumarian encyclopedic knowledge of the life force. Here the officiant Priest sits before supplicant initiates eager to gain esoteric knowledge. They approach the stage with prayerful postures and are allowed to first learn by touching the charged table.
Pine cone non-conductors are often held by participants as protective shields against cross body electrical discharges that might stop heart activity.
Read 10 tweets
Laurence Badgley, M.D. Profile picture
May 21, 2025
WELLNESS RETREAT HAWAII: @starr59366

sites.google.com/view/longcovid…
sites.google.com/view/longcovid…
NATURAL THERAPIES:
we have entered an era where there will be greater emphasis on the use of natural energies to bolster human wellness.
Read 4 tweets
Laurence Badgley, M.D. Profile picture
Apr 12, 2025
He holds an ANK electricity resonator above a Djed pillar electrical capacitor which has gathered pizeoelectric energy from the gigantic limestone crystals that composed the pyramids, where the static electricity is represented as spouts of leaves about he pillar. He holds a staff that is proximally made of non-conductive wood, to protect his body from electrical flow through his heart. The assistant uses a hook to lower the distal staff of made of metal and drawn downward to complete an electrical circuit, thereby enabling electricity to flow to the upward left conduit, probably into the ubiquitous “battery” bags within many of these carved reliefs of secret priestly instructions.
The large blocks of limestone were shaken by rivers of water, described in ancient literature, to flow into the pyramid tunnels which ended in blind pockets, and the intermittent flows were controlled by flood gates. The percussions of water shook the giant stones creating electrical energy gathered into the Djed pillar capacitors wherefrom priests directed the energy into metal conductors and into clay and metal battery bags for storage. The Egyptians were metal smiths.
The Deij pillars heated up at the top, and the hieroglyphic reliefs show rounded items at the top of the pillars. This was calcium calcite, which when heated gives off a lime colored light which was used to light the inside of pyramids. Certainly lighted torches were unusable for lighting for the sculptors because of emitted smoke.
Read 6 tweets
Laurence Badgley, M.D. Profile picture
Mar 31, 2025
ANCIENT ELECTRICITY: winged couriers carried battery bags that had been charged in pyramids by priests. As they carried the charged devices they needed to avoid grounding their upper bodies from static discharges & electricity through heart. Pinecones were non-conductors that fit the hand to remind them. My speculation.
The wreath of flowers to the left represents the feeling of static electricity and the same flowers are often part of pyramid Deij pillar hieroglyphics which concentrate electrical energy inside the giant pyramids.
Image
Read 10 tweets

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