Laurence Badgley, M.D. Profile picture
Sep 7, 2019 19 tweets 5 min read Read on X
Twitter thread about these relationships follows:
ANXIETY AND PANIC ATTACKS:
I have my own theories about these disorders in those with #HSD. Panic attacks are common in persons with #Fibromyalgia, the patient population I study.
Often people with #Fibromyalgia come to me by way of federally-funded clinic Psychologists, who are treating them for psychologic disorders. They want me to prescribe major psych meds.
Many of these patients have been diagnosed with major depression & sent for anti-depression meds. Their underlying #Fibromyalgia has not been detected & no one has asked them about their average total nightly sleep time nor number of awakenings.
Patients with #Fibromyalgia sleep like “rotisserie chickens”. They toss and turn & sleep about 3-5 hours total; with several awakenings. Their sleep is interrupted by pain & is non-restorative of brain function. Daytime fatigue & naps are common.
Many of these patients have been diagnosed with major depression & sent for anti-depression meds. Their underlying #Fibromyalgia has not been detected & no one has asked them about their average total nightly sleep time nor number of awakenings.
Many of these patients surface sleep & rarely dream.
Patients with restless sleep are cognitively confused (foggy) & will go into rooms forgetting why. The major consequence of non-restorative sleep is Depression. Neurologists know this, or should. Loss of sleep induces anxiety & worry over inability to reverse downward mood slides
Many persons with #HSD have vertebral spine scoliosis when upright (disks are ligaments). I regard that functional scoliosis might induce impingements of contiguous ANS sympathetic chain, resulting in cardiac rhythm changes & gastric dysfunctions, i.e., Gastroparesis.
Functional scoliosis can be observed by companions of patients. Simply slide 2 fingers down sides of spine. Patient can look in mirror to see one shoulder lower.
Many persons with #HSD have Mitral Valve Prolapse (MVP). Mitral valves of heart are made of cartilage/connective tissue; when floppy can lead to incompetence & loss of forward blood flow when going upright. MVP is not a disease, but a functional disorder.
Another #HSD tissue variation is loss of venous vessel wall cartilage/connective tissue/muscle firmness & contractility. When patients go upright, blood pools in lower extremities depriving brain; causing head rushes & even syncope.
When the brain senses low pressure of blood flow it has options: cause syncope & render body tower horizontal so blood more easily flows to brain. Dystonic flailing are common with syncope & can be misinterpreted as “seizures”; later studied as “pseudoseizures”.
Another option of brain being deprived of oxygenated blood is for autonomic NS (sympathetic) to race heart & lungs, with symptoms experienced as shortness of breath & tachycardia. The person feels like they are about to die. This is called a Panic Attack.
Persons wPanic Attacks & absent laboratory findings (anemia, thyroid, etc.) worry doctors, who then consider psychologic issues; with Psychologist/Psychiatrist referrals to investigate. What these patients really need is cardiac ultrasound to visualize mitral valve in real time.
Those who have frequent syncope need to be referred to a Cardiologist & evaluated for Postural Orthostatic Tachycardia Syndrome (POTS). Psychologic issues are diagnoses of exclusion.
Once branded with psychological problems, many patients have difficulty ever finding a doctor to consider alternative diagnoses; much less to elicit history & stigmata of hypermobility.
A suggestion for patients is to bring wiki-type print outs of problems to doctor. If Dr. dismisses your input & takes not time to describe reasoning for diagnosis, you need to regard excess doctor-ego & find another physician (means “teacher” in Greek).
If the reader has interest in clinical medical references there are none; except for my previous publications. The theories and physiological dynamics offered above are my own novel inventions, and based on countless empirical clinical observations.

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More from @BadgleyLaurence

Apr 16
LOOSE JOINTS, HYPERMOBITY? Gravity is at play in these women with tissue variations. When joint are unstable the obvious compensation is “gorilla” muscles to take over lax ligament efforts. A wise Physical Therapist is key. Lots of dedicated exercise also.
LOOSE JOINTS INHERITED (-15% women) is normal. These woman’s have easier births & indigo-smart children. These women are often quite attractive and smart.
ABORIGINAL SOCIETIES
CHERISHED HYPERMOBILE
WOMEN BECAUSE THEY WERE SMART & PROLIFIC BIRTHERS. INTELLIGENCE GENES LIKELY GROUP WITH HYPERMOBILITY GENES & GENES FOR BEAUTY. MEN WANTED FECUND ATTRACTIVE WOMEN SO THEY SELECTED THEM OUT.
Read 6 tweets
Apr 14
HYPOPERFUSION? Yes, maybe sympathetic nervous system dominance + decreased pituitary vasopressin causing excess free water elimination in urine ⏩️ decreased blood circulation of hyperosmolar blood.
COVID-CAUSED decreased blood volume of blood that is too thick might explain orthodtstic hypotension, POTS. Might also explain the wormy blood clots.
COVID-CAUSED diminished total blood volume might evoke sympathetic nervous system activation to prevent hypotension and prevent syncope. Diminished blood volume would be expected to deliver less oxygen to tissues ⏩️ fatigue & exercise intolerance.
Read 5 tweets
Apr 9
TO BE GAY ON NOT, THE QUESTION? In ancient days of the mid last century, the proper medical terminology was “homosexual”. Homo is a Greek prefix for “man” such as used in our species name, homosapiens, I think. Along the way a new adjective/noun, a euphemism, was created, “gay”.
“GAYNESS” might be adverb. I don’t know, grammar not my long suit. In any case, Anthropologist of last century seemed to be of consensus that a fixed ~15% of the population was homosexual as a transcultural genetic characteristic of homosapiens. Indeed, genes direct hormones.
TO BE GAY OR NOT: THE “GREAT H & E DEBATE” (heredity vs. environment) is a dynamic that has ever lent unending entertainment and fascination to the study of the human condition & especially to the world of medical studies.
Read 7 tweets
Apr 6
MCAS IN LONG COVID: is possibly etiologic via biomechanisms known about MCAS, HYPERMOBILITY (HS) & FIBROMYALGIA (FM). Persons with HS & FM commonly suffer MCAS. Reason has been theorized that mast cells reside proximate connective tissue.
MCAS, HS, & FM: hyperflexible connective tissue evokes mast cell degranulation. Reactive substances provoke proximate neural tissues. Some experimental data for this dynamic. It might be that those with long COVID & MCAS expression might have hypermobility (about 15% women).
Read 11 tweets
Mar 12
IC CAUSE DISCOVERED: for years clinicians have been mystified by etiology of IC. Genes, microbes, toxins, & biochemistry have failed to provide insights. IC oft occurs in women who have Hypermobility Syndrome and/or IBS. These circumstances suggest that IC is a dysautonomia.
IC A DYSAUTONOMIA? parasympathetic part of autonomic system stimulates smooth tissues of bladder & bowel to contract/evacuate those organs. Over activity of this neural network is unmeasurable, as yet, in current medical sciences. Absence of evidence is not evidence of absence.
IC CLINICAL DATA: hypermobile women are potentiated for developing pelvic girdle instability from loose sacroiliac joint (SIJ) ligaments & are prone to Mast Cell Activation Syndrome (MCAS). Dr. Afrin’s book explains MCAS. I published case studies of IC remission via SIJ fusion.
Read 9 tweets
Mar 12
IRRITABLE BOWEL SYNDROME: doctors will tell you the cause is “unknown”. This is not true. IBS is commonly found in women either Hypermobility Syndrome. Reason is that these women are prone to pelvic girdle injuries and ligament laxity of one of the sacroiliac joints.
IBS & HYPERMOBILITY SYNDROME: This association well known in medical circles. Some of these women have regular daily frequent loose stools. Some have intermittent episodes of several days of constipation. Another set of these women have alternating constipation and loose stools.
IBS EXPLAINED: reason cause is “unknown” is that anatomical, tissue, and biochemical explanations are unknown and wanting. However, the dysfunction of the bowel suggests the cause is dysfunction of the autonomic nervous system, the parasympathetic and sympathetic.
Read 14 tweets

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