Share this page!

Enter URL or ID to Unroll

You can paste full URL like: https://x.com/threadreaderapp/status/1644127596119195649
or just the ID like: 1644127596119195649

How to get URL link on X (Twitter) App

  1. On the Twitter thread, click on or icon on the bottom
  2. Click again on or Share Via icon
  3. Click on Copy Link to Tweet
  4. Paste it above and click "Unroll Thread"!
  5. More info at Twitter Help
Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
@edgarvlermamd
Dec 13, 2019 β€’ 27 tweets β€’ 34 min read β€’ Read on X
Scrolly
.@goKDIGO Controversies Conference on Optimal Anemia Management in CKD
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ kdigo.org/wp-content/upl… Image
Mechanisms of anemia in CKD ca. 2012 from @JASN_News
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ jasn.asnjournals.org/content/jnephr… ImageImage
Update on Anemia in ESKD and Earlier Stages of CKD: Core Curriculum 2018 from @AJKDonline @sfishbane
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ ajkd.org/article/S0272-… ImageImageImageImage
Potential mechanism of increased CV risk with higher hemoglobin targets in ESA studies
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ ncbi.nlm.nih.gov/pmc/articles/P… ImageImage
Anemia in CKD: ESA trials
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls #NephSecrets ImageImage
Hypoxia-inducible factor (HIF) gene targets
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ ncbi.nlm.nih.gov/pmc/articles/P… ImageImage
PIVOTAL: Among patients undergoing hemodialysis, a high-dose IV Fe regimen administered proactively was superior to a low-dose regimen administered reactively & resulted in lower doses of ESA being administered from @NEJM
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ nejm.org/doi/pdf/10.105… ImageImage
Crosstalk between iron and oxygen sensing
πŸ“Œ HIF-dependent gene expression is iron dependent
πŸ“Œ Iron-absorbing genes are HIF target genes
πŸ“Œ FPN stabilizes HIF-2 in enterocytes
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ kidney-international.org/article/S0085-… Image
Prevalence of anemia of CKD in the US πŸ‡ΊπŸ‡Έ
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ journals.plos.org/plosone/articl… ImageImageImage
Traditionally used markers of iron status, ⬇️ TSAT, especially TSAT< 10%, is most strongly associated with the risk of adverse outcomes in CKD patients irrespective of serum ferritin level
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ bmcnephrol.biomedcentral.com/track/pdf/10.1… ImageImage
Causes of absolute iron deficiency
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ kdigo.org/wp-content/upl… ImageImage
Suggested management of reactions to IV iron
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ kdigo.org/wp-content/upl… ImageImageImageImage
HIF in the regulation of FGF23 ca. 2019 from @NatRevNeph
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ nature.com/articles/s4158… ImageImage
Effects of Molidustat in the Treatment of Anemia in CKD ca. 2019 from @CJASN
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ cjasn.asnjournals.org/content/clinja… ImageImage
Daprodustat produced dose-dependent changes in hemoglobin over the first 4 weeks after switching from a stable dose of rhEPO as well as maintained hemoglobin target levels over 24 weeks
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ academic.oup.com/ckj/article/12… ImageImage
Vadadustat, a novel oral HIF stabilizer, provides effective anemia treatment in nondialysis-dependent CKD
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ kidney-international.org/article/S0085-… ImageImageImage
List of Oral Iron Agents Used for Treating Anemia in Patients With CKD ca. 2019
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ ackdjournal.org/article/S1548-… ImageImage
Iron Preparations in the Treatment of Anemia in Non-Dialysis Dependent CKD ca. 2019
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ ackdjournal.org/article/S1548-… ImageImageImage
Iron Preparations in the Treatment of Anemia in Dialysis Dependent CKD ca. 2019
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ ackdjournal.org/article/S1548-… ImageImageImage
Roxadustat for Anemia in CKD | @NEJM
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ“Ί nejm.org/do/10.1056/NEJ… ImageImageImageImage
Pathogenesis of renal anemia and novel and emerging therapies
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ jasn.asnjournals.org/content/jnephr… ImageImageImage
Diagnostic tests and therapeutic targets 🎯 for anemia of CKD
#KDIGOAnemia πŸ‡ͺπŸ‡Έ #Nephpearls
πŸ‘‰πŸΌ kdigo.org/wp-content/upl… ImageImageImageImage
HIF PHD inhibitors in clinical development ca. 2019
#Nephpearls #Welcome2020
πŸ‘‰πŸΌ asn-online.org/publications/k… ImageImage
Check out πŸ‘‰πŸΌ Hypoxia-inducible Factor (HIF) Stabilizers for Treating Anemia of CKD

πŸ“Œ This is my choice for ⚑️Kidney Watch 2020⚑️ published in the February 2020 issue of @KidneyNews

#Nephpearls
πŸ‘‰πŸΌ asn-online.org/publications/k… ImageImageImage
Landmark Trials in Anemia and CKD from @RenalFellowNtwk @xaviervel @landmark_neph #Nephpearls
πŸ‘‰πŸΌ renalfellow.org/2020/02/19/lan… Image
Effect of Ferric Citrate versus Ferrous Sulfate on Iron and Phosphate Parameters in Patients with Iron Deficiency and CKD ca. 2020 from @CJASN #Nephpearls
πŸ‘‰πŸΌ cjasn.asnjournals.org/content/clinja… ImageImageImageImage
Oral daprodustat was noninferior to darbepoetin alfa as measured by mean hemoglobin over weeks 40–52 in Japanese πŸ‡―πŸ‡΅ patients receiving hemodialysis switched from ESAs ca. 2020 from @CJASN #Nephpearls
πŸ‘‰πŸΌ cjasn.asnjournals.org/content/clinja… ImageImageImageImage

β€’ β€’ β€’

Missing some Tweet in this thread? You can try to force a refresh
γ€€

Keep Current with Edgar V. Lerma πŸ‡΅πŸ‡­

Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @edgarvlermamd

Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Feb 26, 2022
Advancing Evidence-Based Care in Diabetes and CKD
#ISNWCN πŸ‡²πŸ‡Ύ #Nephpearls

πŸ‘‰ kdigo.org/wp-content/upl…
Holistic approach for improving outcomes in patients with Diabetes and CKD
#ISNWCN πŸ‡²πŸ‡Ύ #Nephpearls
Glucose-lowering agents in Type 2 Diabetes (T2D) and CKD: Indications and dose adjustments
#ISNWCN πŸ‡²πŸ‡Ύ #Nephpearls
Read 9 tweets
Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Feb 26, 2022
.@goKDIGO Glomerular Diseases Guideline: Reflections on a Decade of Progress with @adrianliew8 @ReichHeather @Dr_KeishaGibson
#ISNWCN πŸ‡²πŸ‡Ύ #Nephpearls

πŸ‘‰ kdigo.org/wp-content/upl…
IgA Nephropathy: A 1st step is in treating IgA Nephropathy is assessing "prognosis" based on data available at the time of biopsy

@goKDIGO suggest using the "prediction tool" that was derived from the largest & most geographically diverse cohort to date

#ISNWCN πŸ‡²πŸ‡Ύ #Nephpearls
IgA Nephropathy: The @goKDIGO treatment algorithm recommends consideration of use of corticosteroids in patients with "persistent proteinuria >1g/day" if the risk/benefit profile is favorable

πŸ“Œ A GFR of 30 is considered a threshold for treatment

#ISNWCN πŸ‡²πŸ‡Ύ #Nephpearls
Read 13 tweets
Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Feb 23, 2022
First clinical-grade porcine πŸ– kidney xenotransplant using a human decedent model ca. 2022 from @amjtransplant #NephJC #Nephpearls

#VisualAbstract by @NamrataYParikh

πŸ‘‰πŸΌ pubmed.ncbi.nlm.nih.gov/35049121/ Image
Attitudes to Clinical Pig Kidney Xenotransplantation among Medical Providers and Patients ca. 2020 from @ASNKidney360 #Nephpearls

kidney360.asnjournals.org/content/1/7/657 ImageImage
Paving the Path toward Porcine Organs for Transplantation ca. 2017 from @NEJM #NephJC #Nephpearls

nejm.org/doi/full/10.10… ImageImage
Read 4 tweets
Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Jan 30, 2022
Nephrolithiasis 101: When to order a 24-hour urine collection #Nephpearls

Multiple or metabolically active stones (stones that increase in size/ number w/in a year)

Children

Demographic groups not typically prone to stone formation

Stones other than those containing calcium ImageImage
Interpretation of urine chemistries to identify lithogenic risk factors and assess the contribution of diet to the formation of kidney stones ca. 2016 from @ravineja #Nephpearls

sciencedirect.com/science/articl… Image
Neglected analytes in the 24 hour urine: ammonium and sulfate ca. 2021 from @CO_Neph_Hype @ravineja #Nephpearls

πŸ‘‰ pubmed.ncbi.nlm.nih.gov/34798636/ ImageImageImageImage
Read 4 tweets
Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Jan 26, 2022
PREDNOS 2: Evaluation of Daily Low-Dose Prednisolone During URTI to Prevent Relapse in Children w/ Relapsing Steroid-Sensitive Nephrotic Syndrome ca, 2022 from @JAMAPediatrics #NephJC #IPNAJC #Nephpearls

#VisualAbstract by @drM_sudha

jamanetwork.com/journals/jamap…
Low-dose versus conventional-dose prednisolone for nephrotic syndrome relapses: a randomized controlled non-inferiority trial ca. 2022 from @Ped_Neph #NephJC #IPNAJC #Nephpearls

#VisualAbstract by @md_abdulqader83

link.springer.com/article/10.100…
PREDNOS: Sixteen-week versus standard eight-week prednisolone therapy for childhood nephrotic syndrome ca. 2019 from @bmj_latest #NephJC #IPNAJC #Nephpearls

#VisualAbstract by @jbda19

pubmed.ncbi.nlm.nih.gov/31156083/
Read 5 tweets
Edgar V. Lerma πŸ‡΅πŸ‡­ Profile picture
Nov 17, 2021
Clinical Practice Guideline for the Management of Glomerular Diseases ca. 2021 from @goKDIGO #NephJC #Nephpearls
#VisualGraphics by @michaelturk6

Executive Summary pubmed.ncbi.nlm.nih.gov/34556300/
Full Guideline pubmed.ncbi.nlm.nih.gov/34556256/
The spectrum of glomerular diseases from @neilturn #NephJC #Nephpearls

πŸ‘‰ global.oup.com/academic/produ…
Nephrotic range proteinuria does "not always" mean nephrotic syndrome #NephJC #Nephpearls

πŸ‘‰ pubmed.ncbi.nlm.nih.gov/34556256/
Read 4 tweets

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

Send Email!

:(