Craig Spencer MD MPH Profile picture
Mar 24, 2020 18 tweets 4 min read Read on X
Thank you everyone for your incredible messages of support and encouragement.♥️

Many of you asked what it was like in the ER right now. I want to share a bit with you. Please RT:

A Day in the Life of an ER Doc - A Brief Dispatch from the #COVID19 Frontline:
Wake up at 6:30am. Priority is making a big pot of coffee for the whole day, because the place by the hospital is closed. The Starbucks too. It's all closed.

On the walk, it feels like Sunday. No one is out. Might be the freezing rain. Or it's early. Regardless, that's good.
Walk in for your 8am shift: Immediately struck by how the calm of the early morning city streets is immediately transformed. The bright fluorescent lights of the ER reflect off everyone's protective goggles. There is a cacophony of coughing. You stop. Mask up. Walk in.
You take signout from the previous team, but nearly every patient is the same, young & old:

Cough, shortness of breath, fever.

They are really worried about one patient. Very short of breath, on the maximum amount of oxygen we can give, but still breathing fast.
You immediately assess this patient. It's clear what this is, and what needs to happen. You have a long and honest discussion with the patient and family over the phone. It's best to put her on life support now, before things get much worse. You're getting set up for that, but...
You're notified of another really sick patient coming in. You rush over. They're also extremely sick, vomiting. They need to be put on life support as well. You bring them back. Two patients, in rooms right next to each other, both getting a breathing tube. It's not even 10am yet
For the rest of your shift, nearly every hour, you get paged:

Stat notification: Very sick patient, short of breath, fever. Oxygen 88%.

Stat notification: Low blood pressure, short of breath, low oxygen.

Stat notification: Low oxygen, can't breath. Fever.

All day...
Sometime in the afternoon you recognize you haven't drank any water. You're afraid to take off the mask. It's the only thing that protects you. Surely you can last a little longer - in West Africa during Ebola, you spent hours in a hot suit without water. One more patient...
By late afternoon, you need to eat. Restaurant across the street is closed. Right, everything is closed. But thankfully the hospital cafeteria is open. You grab something, wash your hands (twice), cautiously take off your mask, & eat as fast as you can. Go back. Mask up. Walk in.
Nearly everyone you see today is the same. We assume everyone is #COVIDー19. We wear gowns, goggles, and masks at every encounter. All day. It's the only way to be safe. Where did all the heart attacks and appendicitis patients go? Its all COVID.
When your shift ends, you sign out to the oncoming team. It's all #COVIDー19. Over the past week, we've all learned the signs - low oxygen, lymphopenia, elevated D-dimer.

You share concerns of friends throughout the city without PPE. Hospitals running out of ventilators.
Before you leave, you wipe EVERYTHING down. Your phone. Your badge. Your wallet. Your coffee mug. All of it. Drown it in bleach. Everything in a bag. Take no chances.

Sure you got it all??? Wipe is down again. Can't be too careful.
You walk out and take off your mask. You feel naked and exposed. It's still raining, but you want to walk home. Feels safer than the subway or bus, plus you need to decompress.

The streets are empty. This feels nothing like what is happening inside. Maybe people don't know???
You get home. You strip in the hallway (it's ok, your neighbors know what you do). Everything in a bag. Your wife tries to keep your toddler away, but she hasn't seen you in days, so it's really hard. Run to the shower. Rinse it all away. Never happier. Time for family.
You reflect on the fact that it's really hard to understand how bad this is - and how bad its going to be - if all you see are empty streets.

Hospitals are nearing capacity. We are running out of ventilators. Ambulance sirens don't stop.
Everyone we see today was infected a week ago, or more. The numbers will undoubtedly skyrocket overnight, as they have every night the past few days. More will come to the ER. More will be stat notifications. More will be put on a ventilator.
We were too late to stop this virus. Full stop. But we can slow it's spread. The virus can't infect those it never meets. Stay inside. Social distancing is the only thing that will save us now. I don't care as much about the economic impact as I do about our ability to save lives
You might hear people saying it isn't real. It is.

You might hear people saying it isn't bad. It is.

You might hear people saying it can't take you down. It can.

I survived Ebola. I fear #COVIDー19.

Do your part. Stay home. Stay safe.

And every day I'll come to work for you

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More from @Craig_A_Spencer

May 23
I've spent a lot of the last week speaking to people across government, media, and other actors involved in the Ebola response. Some reflections:
Size of the outbreak: this is massive already. Based on some other signals and conversations, this outbreak is at least 2-3 months old.

Official case numbers are ~1,000. But I suspect the true number is much larger, probably double. This will almost certainly end up being the second largest Ebola outbreak ever, and soon.

There have been 'mysterious' outbreaks close to the current hotspots for some time, and we still don't have a full accounting of all those.

I worked as an epidemiologist during an Ebola outbreak in Guinea in 2015. Tracking this and contract tracing is tough work. It'll take a few more weeks to further understand what communities have already been affected.
Vaccines/Treatments: you've probably heard there are "no treatments of vaccines" for the Bundibugyo species of Ebola.

There's been some movement on moving candidates along—including from Oxford to use the ChAdOx platform for a potential vaccine. Work on that is progressing, but would be many months away.

There's also a rVSVΔG vaccine—using the same platform as the FDA-approved Merck vaccine for Zaire Ebolavirus—that's being discussed, but would also take many months.

We have LOTS of Ervebo, that FDA-approved vaccine for the Zaire species, and there is some discussion about potentially using it here, since it *may* offer some cross-protection. The risk/benefits of that is outside my league...for more, go ask an amazing vaccinologist/immunologist nerd :)

On treatments, there are two monoclonal antibody 'cocktaills' that have promise, and will likely be used here. One by Regeneron and another by Mapp Bio. Doses are limited however, and there will be some logistical hurdles in getting these used quickly.

ox.ac.uk/news/2026-05-2…
Read 8 tweets
Sep 22, 2025
I’m absolutely speechless. Like, wow.

This is the worst ‘health’ press conference I maybe have ever seen

And I watched every one during Covid

How are we doing this again???
How can you be so wrong on so many things in such a short period of time
"We promised transparency"...yet they are announcing a 'ground-breaking' discovery but didn't put out a SINGLE OUNCE OF ANY NEW DATA beforehand.

This is pure persuasion, not peer review

Like, this is so sloppy and dangerous
Read 11 tweets
Aug 6, 2025
Setting aside the MANY scientific inaccuracies he stated to justify the termination of mRNA research...

And recognizing there's already been a lot said on this really horrible decision...

I want to add something here, namely, that RFK Jr is making a really dangerous gamble 🧵
The termination of $500 million in mRNA contracts is an absolutely bone-headed move.

We will be much less prepared for the next health crisis.

There is absolutely no debating that.

Especially piled on the revocation in May of a big contract to develop a bird flu vaccine.
I also want to reiterate, over and over again, that no matter what you think about Covid, the government or state responses, lockdowns, masking etc...

The mRNA Covid vaccines saved a LOT of lives.

Millions in the U.S.

And many more millions around the world.

That's a fact.
Read 11 tweets
Jun 26, 2025
Everyone’s saying cutting GAVI funding means more diseases will come to the U.S.—and that's true.

Others are pointing out a LOT of kids will die—also true!

But everyone’s missing the most important part of this video—this is RKF Jr taking his anti-vaccination crusade global 🧵
For the record, GAVI has been incredible.

Co-founded by the US back in 2000, GAVI has saved MILLIONS of lives around the world

All by making vaccines to kids—to date, they've vaccinated over a billion children.

I go deeper into GAVI here 👇

In today's video announcing the U.S. is withdrawing its previous funding commitment to GAVI, RFK Jr spends more time attacking vaccines than GAVI itself.

And he justifies the death of millions of children because he didn't like GAVI's social media policies on Covid vaccines. Image
Read 10 tweets
Jun 10, 2025
I was seeing patients in the ER when I got a text from a friend

"How bad is this thing about RFK Jr removing ALL 17 experts from a CDC vaccine advisory committee?"

Theres been a lot of hot takes on here already

But heres why this makes me worry, from a clinical perspective 🧵
For background, if you haven't heard yet:

There are 17 members of an advisory committee on immunization practices at the CDC. It's called ACIP.

It's made up of brilliant volunteers who review reams of data and make recommendations on vaccines.

They all got booted today.

hhs.gov/press-room/hhs…
There was almost unanimous rebuke from clinical organizations that should give us all pause.

These are the doctors that take of every American — from obstetricians to pediatricians to family practitioners—that ALL came out today to denounce RFK's move today.
Read 13 tweets
May 30, 2025
There were disturbing developments this week that will undoubtedly affect your health.

But most people didn't notice, because they weren't so splashy, or may not seem like a big deal.

But I want to talk to you about each of them, why they matter, and why we should be worried:
Earlier this week, RFK Jr stood alongside the FDA and NIH directors and announced a change in COVID vaccine recommendations...

On X. And only X.

No reports, no science, no reflection on the discussion or decision-making process behind this.

This is very concerning...
Over and over, RFK Jr promised 'radical transparency'.

But the process here is just radical.

His official announcement—by tweet—is that Covid vaccines are no longer recommended for kids and pregnant women.

There were scant details. And he doesn't discuss the data, at all.
Read 15 tweets

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