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Anecdotal reports of inflammatory circulatory problems in skin.

Chronic spontaneous urticaria involves plasma leakage, edema, activation of clotting factors, hives, redness.

Genuine frostbite includes varying degrees of coagulation within damaged area.
francebleu.fr/amp/infos/sant…
Further similar case reports from France. Suspect peripheral microthrombosis:



@farid__jalali
Instances of this peripheral blood vessel damage now being reported from France, Spain, Italy, and elsewhere:

dermapixel.com/2020/04/covid1…

Apologies to followers for slightly unsettling imagery; attempting to provide a useful compilation for medical staff.

Also useful for patients to watch for such symptoms if they appear. Stronger evidence for COVID-19 over other infections. Inflammation of capillary walls.
Translations from the linked Spanish article for convenience. Includes many more representative examples.

The author likewise believes them to originate from ischemia secondary to microthrombosis in the extremities--
Further detail from some of the Italian reports--

Another one, courtesy of @MarcosMaurelli

@dartsandmonkeys this is the main thread for COVID-19 acro-ischemia and related suspicious findings in extremities.

It hints at vascular endothelial dysfunction even early in the course or in some mild cases.

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