1/5 Both Atherosclerosis and Alzheimer’s disease (AD) bear some striking similarities. In the case of AD amyloid beta Aβ is (an antimicrobial peptide), an innate immune defense molecule that utilizes fibrillation, & tries to protect the host from a wide range of free radical
2/5 damage and infectious agents. In the case of Atherosclerosis various lipoproteins which are part of the innate immune response come to the rescue. In AD studies have shown that HIV infection increases intra and possibly extracellular amyloid beta.
3/5 There are also a many studies pointing to infection as a contributor in Atherosclerosis.
I think we need to stop laying the blame on amyloid beta and cholesterol. Anti-amyloid drugs don’t work for AD, and cholesterol lowering drugs (statins) don’t work
I think we need to stop laying the blame on amyloid beta and cholesterol. Anti-amyloid drugs don’t work for AD, and cholesterol lowering drugs (statins) don’t work
4/5 for Atherosclerosis. The simple reason is that high cholesterol, and amyloid beta are not causal. We need to look at such things as mitochondrial abnormalities involved in cellular energetics, the cytokine-induced changes in both the structure and function of lipoproteins,
5/5 oxidative stress/free radical damage, microbiome & gut dysbiosis, infection, calcium etc, and also look at the possibilities of CoQ10 and vitamin E protecting cell membranes from lipid peroxidation. Just my humble opinion ….@DrPaulMason
jnmjournal.org/journal/view.h…
jnmjournal.org/journal/view.h…
