Marion Holman Profile picture
Follow the science not the $$ - Diet & lifestyle over pharma drugs. Love nature, walking and dogs
The Real Dr. Steven Horvitz Profile picture dr roth ⓀⒸ Profile picture Murphy Kismet Morgan Profile picture Paul Melzer Profile picture GD Fraser Profile picture 8 added to My Authors
26 Sep
1/ Reasons why I don't trust Docs or pharma drugs:
Me age 30, diagnosed with severe Osteoporosis after a bone scan. Nurse told me I had the bones of a 70 yr old. They put me on Bisphosphonates. I researched

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2/ these drugs, and realised that they caused necrosis of the jaw, stomach irritation etc. Sooo I decided to do some more research, and what did I find ? Low and behold, Vitamin D3 and Vitamin K2 (MK7) puts calcium where it meant to be, in the BONES not the ARTERIES.
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3/ I never looked back. I've had falls from climbing, hard falls, & never broken a bone,. However a friend who has taken Bisphosphonates for the past 2 years recently had an accident. A minor fall from a restaurant stool, which resulted in a very complex break requiring

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Read 4 tweets
26 Sep
1/ Here we have Peter Attia discussing the THEORETICAL😂 possibility that lipid-lowering drugs MIGHT negatively impact cognitive function, and specifically, whether PCSK9 inhibitors had such an impact. The answer, according to him, appears to be NO. 🙄

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2/ Now I really have to wonder if Attia has some conflict of interest with Amgen, Regeneron and Sanofi since PCSK9’s reduce LDL-C by a massive 50%+. You just have to think - why did he say this ?

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/3 Undoubtedly, Statins prevent the body from making an antioxidant that neutralizes the damaging free radicals created by mitochondrial activity. If brain cells—which consume lots of energy—already have mitochondrial problems, then STATIN ‘ therapy’

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Read 6 tweets
13 Sep
1/ We show that Statin-induced insulin resistance is a drug CLASS EFFECT. Cerivastatin was removed from the market because of "side effects". Our results show that Cerivastatin was the most potent Statin in promoting adipose insulin resistance.

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2/ "We show that statins impaired insulin-stimulated lipogenesis in an adipocyte-autonomous manner, which was prevented by supplementing isoprenoids required for prenylation". WHY ??

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3/ because Statins interfere with the Mevalonate pathway & deplete so many organic compounds with great structural diversity and functionality.

- and you can't always put back what Statins stole in the first place. The overriding message is
Stay away from Statins.
Read 4 tweets
9 Sep
1/ Apoptosis (cell death) is an essential component of the maintenance process of our bodies. It is a highly controlled and regulated technique for removing unwanted cells from any organ by the process of induced metabolic suicide.

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2/ Tinkering with this process is a potentially catastrophic game. This is the game of Russian Roulette that we play when we take Statins.
That good old law of unintended consequences could have a field day here.

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3/ Statins promote apoptosis. They do it in diseased tissues - Cheers for Statins. Unfortunately they ALSO do it in NORMAL tissues too; Boo for Statins.
Read 8 tweets
9 Sep
1/ Where do you find the highest concentration of cholesterol in your whole body ? YUP ! In your brain.

Although the brain represents only 2% of total body weight, it contains 20% of the body’s cholesterol. What is all that cholesterol doing up there ?
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2/ Synapses - where communication between brain cells takes place are lined by cholesterol-rich membranes responsible for passing neurotransmitters like serotonin, GABA, and dopamine back and forth.

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3/ Myelin, the white matter that insulates brain circuits, is made from tightly-wound membranes containing 75% of the brain’s cholesterol. Cholesterol also helps guide developing nerve endings to their destinations on “lipid rafts”.
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Read 4 tweets
5 Sep
1/ Someone sent me a DM a few days ago "what range should our cholesterol be" ? I think it’s important to stress that cholesterol reference ranges are merely an average of the general population, and that traditional populations with NO heart disease have healthy cholesterol

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2/ levels which are often much much HIGHER than the baselines for Western Societies. Reversing insulin resistance by lowering fasting blood sugar, and lowering inflammation by dietary changes is a far more sensible approach than lowering cholesterol.

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3/ Total cholesterol is a TOTALLY MEANINGLESS number, since it doesn’t tell you what that cholesterol is made up of, but guidelines say it should be around
250mg/dL - ( 6.465 mmol/l)

LDL cholesterol 130mg/dL ( 3.3618 mmol/l)

HDL cholesterol 60mg/dL (1.5516 mmol/l)

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Read 5 tweets
2 Sep
1/ GABAPENTIN ! Yeah another great drug according to Docs and Veterinary surgeons: "This is what I have since learned about the drug: Stanford University did a study on gabapentin in 2009 and found that it prevents the formation of new synapses in the brain.
2/ Many who take it long-term eventually develop cognitive impairment and short-term memory loss. Gabapentin affects GABA (gamma-aminobutyric acid—a “calming” element) in the body. When taking the drug, one’s body will adjust to the artificially induced GABA and start to

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3/ produce less of its own. (That fact is similar to benzodiazepines except that gabapentin affects GABA through calcium receptors rather than GABA receptors.)

Though not technically addictive, dependency can happen very quickly. If taken incorrectly, stopped abruptly,

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Read 6 tweets
2 Sep
1/ SOS ! Can any of my followers or anyone connected to the veterinary industry help me.? If not can you please give this an RT to reach out. I have a friend who has a dog which has Osteosarcoma. It has now been revealed that there is a hairline crack in the bone.
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2/ It has been suggested that intravenous Bisphosphonate treatment is the solution. I disagree because I did my research years ago when I was diagnosed with Osteoporosis. What I found was that Bisphosphonates increase mineralisation and reduce the ability to absorb energy

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3/ which could result in accumulation of micro-cracks. The mechanism by which BPs cause osteonecrosis is probably due to a combination of decreased bone remodelling, poor wound healing, and an antiangiogenic effect leading to ischaemic changes and subsequent

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Read 5 tweets
1 Sep
1/ WTH ? They seem to be basing PCSK9 inhibitors on cardio-protection in PCSK9 knockout phenotype. That's a huge leap of faith ! - knockout of genes has pleiotropic effects. Inhibiting their products can have completely different and unexpected effects.

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2/ The PCSK9 gene plays a part in the regulation of blood pressure, and has many other functions I guess they conveniently overlooked that.

Look at the case of Ezetimibe, the last drug approved without outcomes data. Billions were spent on a drug with minimal

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3/ to no effect on outcomes. What were the benefits missed of those billions? Healthcare budgets are limited. If we spend money on unproven drugs, we aren't spending it on cardiac rehab programs, parks, bike lanes, honest school nutrition programs, and many other useful

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Read 5 tweets
31 Aug
1/ This is soo funny. I hope that people like @mosca_matthew are following this: Thomas Dayspring of Wayne, a lipidologist who helps patients prevent CVD by reducing fats like cholesterol in their blood, said the FDA "highly regulates" physician education materials.

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2/ "In addition to the indications and benefits of their medications, all adverse side effects must also be disclosed," Dayspring said. "The programs are fair and balanced." 😂😂

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3/ GlaxoSmithKline paid Dayspring $203,200 from January 2009 to June 2010, making him the second-highest earner in New Jersey, according to the database. He said he frequently lectures on Lovaza, which is "the only FDA-approved, prescription-strength fish oil available."

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Read 4 tweets
29 Aug
1/ The science was, and still is, irrefutable. Blocking the Mevalonate pathway is an exceedingly bad idea. The lipid hypothesis had been discarded when MER/29 (Triparanol) demonstrated that Statins were untenable. Triparanol MER/29 was withdrawn in 1962
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2/ due to severe adverse effects such as nausea & vomiting, vision loss due to irreversible cataracts, alopecia, skin disorders, muscle damage and accelerated atherosclerosis, YES accelerated atherosclerosis !!!!

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3/ Were greed and lust for power really enough to overcome the consciences of what had once been good men and solid scientists ? Could the entire medical establishment be so easily duped and corrupted ?

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Read 5 tweets
22 Aug
1/ Just finished reading “A Statin Free Life” by @DrAseemMalhotra. A very interesting book and for those of you currently taking Statins who are fearful of stopping Statins, this is a good place to start. If I was doing a review I would give the book 9 out of 10.

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2/ For people who have ditched their Statins, there is great comfort and reassurance that you have made the right decisions so far. There is a case study which starts on page 54, of a Pilot who had a heart attack and was prescribed the standard cocktail of drugs
3/ to treat heart disease. He was exceptionally smart/intelligent and he unilaterally decided to cease taking all these medications, despite the fact that he had a 99% blockage in the circumflex artery. The drugs made him so ill that he decided to research

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Read 11 tweets
15 Aug
1/ It is very, very hard to explain how utterly disreputable the lipid hypothesis is. All of this angst about increased LDLc and/or apoB counts on LC diets is based on the assumption that somewhere, somehow, cholesterol is the cause of heart disease.

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2/ How LDLc "invades" (by active and controlled transcytosis!) the sub-endothelial space, disappears from there and then suddenly appears at over 200micrometres deeper, with none showing in the intervening zone requires a belief tenet which bears no resemblance to reality...

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3/ This was bollocks in the 1950s. My question is, as always, at what time did it stop being bollocks?

No one would reasonably doubt that the lipid deep down at the intima/media junction level comes from lipoproteins (though there are other plausible explanations).

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Read 5 tweets
15 Aug
1/ People keep telling me - Marion you are so bloody angry, calm down. How the hell can I when I see countless lives ruined by Statins. Please read this and cry 🤬 It's a posting to the Statins Group on FB. This is not about me, this is another life ruined by Statins:

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2/ "This is what Statins (10 mg Atorvastatin) did to me...I used to hike mountains now I get hoyered to bed and to my reclining chair lift. I'm 100% bedridden now!! I have lost 90-95% of my muscle and almost died. Because of STATINS

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3/ I have HMGCR-NAM (Statin induced necrotizing myositis) Yes. My disease is rare but the muscle loss from statins is not. I had no reason to take Statins I am Diabetic and my Dr said bc im diabetic, high bp and high cholesterol go hand in hand with diabetes.

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Read 5 tweets
15 Aug
1/ Stay with me on this. Read it twice. Fusion allows mitochondria to compensate for one another’s defects by sharing components and thereby helps maintain energy output in the face of stress.

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2/ However, when a certain threshold of damage is reached, mitochondria are eliminated wholesale by autophagy. Fission segregates the most seriously damaged mitochondria to preserve the health of the mitochondrial network in addition to regulating

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3 morphology and facilitating mitochondrial trafficking. The highly dynamic mitochondrial fusion and fission cycle is proposed to balance two competing processes: compensation of damage by fusion and elimination of damage by fission.

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Read 4 tweets
7 Aug
1/ FROM the beginning of the pandemic, herd immunity has been touted as a sort of finish line or Holy Grail at which point the virus runs out steam and true normality returns. it’s necessary to examine the difference between “perfect” vaccines and “leaky” ones.

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2/ Perfect vaccines are so-named because they mimic the perfect immunity that humans naturally develop after having certain childhood disease.
When a vaccine works perfectly, as do the childhood vaccines for smallpox, polio, mumps, rubella and measles,

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3/ It prevents vaccinated individuals from being sickened by the disease, and it also prevents them from transmitting the virus to others. Research demonstrates that the use of leaky vaccines can promote the evolution of nastier ‘hot’ viral strains that put unvaccinated
Read 5 tweets
7 Aug
1/ Get Used to Lockdowns—Iceland is the Canary in the Coal Mine
Iceland has achieved close to 100% vaccination. However, they are learning that the spike protein gene therapy is not like traditional vaccines—it doesn’t establish herd immunity; it spawns viral escape

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2/ (like antibiotics spawn antibiotic-resistant bacteria); and it doesn’t prevent infection, especially for variants that have evolved in infected vaccinees to elude the treatment.

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3/ All of this was predicted by GENUINE scientists (but NOT public health officials) soon after the Pfizer trial results were published.
With COVID cases exploding in Iceland to the worst levels yet, there’s a lot of hand-wringing about the effects of the

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Read 5 tweets
1 Aug
1/ Statin research was founded on scientific assumption and an AGENDA. Statins are dangerous drugs developed in error for profit, Scientific evidence has proven that Statins were lethal Years before the approval of Lovastatin.

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2/ Merck corrupted the science and the scientists.

The approval process was so corrupted by Merck that Lovastatin was bound to be approved.

Merck LIED !

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3/ The approval process was so corrupted by Merck that Lovastatin was bound to be approved. Merck lied. The FDA shirked its duty; neither safety nor efficacy was proven for Statin drugs.

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Read 5 tweets
1 Aug
1/ I've been suffering from the shingles for approx 7 weeks. Things are getting easier, I'm needing less pain relief, so that's a big plus. Imagine if I'd opted for the shingles vaccine 😂😂

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2/ "In an effort to prevent shingles, some patients choose to get a shingles vaccine. However, some of them may have unintentionally contracted the virus from the vaccine.

The shingles vaccine Zostavax can cause many injuries, such as painful shingles, blindness and

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3/ sometimes death. Injured patients have been filing product liability lawsuits against Merck & Co. for failing to provide warnings about the dangers of their vaccine.

From 2006 to 2017, Merck gave 36 million Zostavax doses and earned approximately $685 million per year

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Read 5 tweets
1 Aug
1/ Charcoal is a hot ‘supplement’ these days - and for good reasons. It’s not only the de-gasser’ it’s also showing signs of being a useful as a
“de -cholesterolizer”

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2/ That charcoal might be good at reducing cholesterol has been suggested by a study of patients with Hypercholesterolemia. When these subjects were given 8 grams of activated charcoal 3 x daily for a month, these subjects exhibited an average 25% reduction in total

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3/ cholesterol and an average 41% reduction in LDL cholesterol. Meanwhile HDL went up an average of 8%. The only “side effect” was black stools.

Charcoal is not absorbed by the intestine.

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Read 4 tweets
30 Jul
1/ Desperately looking for some advice from dog owners, or anyone attached to the Veterinary industry.

Have any of you had success treating Osteosarcoma in dogs (apart from the more radical interventions such as amputation or chemotherapy) ?

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2/ Looking at the study below there appears to be a connection between low Vitamin D levels and cancer in dogs. I’m just wondering if any you could pitch in and help ??

hindawi.com/journals/vmi/2…

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3/ Also this:
The primary objective of our study was to determine whether cancer (lymphoma, osteosarcoma or MCT) had a significant correlation with plasma 25(OH)D concentrations in dogs. Results support a relationship between cancer (including all 3 types: osteosarcoma,

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Read 6 tweets