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😷#Flu (is not) in Queensland to 31MAY2020.
Record lowest baseline in 6 years thanks to physical distancing and perhaps related to decreased testing levels as well
Source: health.qld.gov.au/clinical-pract… Image
😷Nationally, Australia has also seen its lowest #flu case numbers (& rates, not shown) in April and May since 2010/2007 respectively (also much less testing was done back then). Image
In Queensland, private lab Sullivan Nicolaides virus testing data shows the same #flu pattern, but adds info about the non-enveloped rhinoviruses (RVs) and adenoviruses. RVs are on the surge (⬆colds and asthma attacks)
snp.com.au/clinicians/res… Image
2018 graph for some comparison (unfortunately raw data aren't easily available for me to make a clearer graph) Image
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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻
@MackayIM
Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis thelancet.com/journals/lance…
"The findings of this systematic review and meta-analysis support physical distancing of 1 m or more "
"From a policy and public health perspective, current policies of at least 1 m physical distancing seem to be strongly associated with a large protective effect, and distances of 2 m could be more effective"
Read 5 tweets
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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻
@MackayIM
What is a false positive coronavirus test? How is it possible? abc.net.au/news/2020-06-0…
"Usually due to a lab being contaminated with the virus or with product from a previous test"
-or clinic
-also sometimes due to quirks of the test; which is why we try to validate well
And to clarify
"Certainly at the moment there was no active infection present, but what may have happened is that it was the end of a previous infection — the test may have detected a little bit of that going on,"
- certainly is too strong a sentence starter.
Just to be clear, I don't have any inside info on the autopsy. It was reported that the deceased "did not have the disease after all" (news.com.au/lifestyle/heal…)
Read 15 tweets
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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻
@MackayIM
@diviacaroline No. That's what that person says to be the case.
If you use kit-based tests, that can be the issue. If you use in-house test there can be PCR product contamination from previous runs that could affect your clean mastermix area, extraction area or template loading area.
@diviacaroline There are also some designs that can give "noise" which can look like late low positive when conditions favour that. There can be weird results when using duplex or triplex or multiplex test that don't show up when using uniplex formats.
@diviacaroline So it can be complex. When using kits rather than in-house tests, you hope that's all been sorted. But I'm seeing some examples where kits have come out with little validation (testing same sample types, samples from same sort of disease, (+) for other viruses) has yet to be done
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