Thread by @kidneyomicsamps

(1/16)THREAD: 18 months ago, Dr. Caroline Fox & I were invited to be co-editors for a @cjasn Special Series on Kidney Disease Genomics. We're so appreciative of the outstanding authors who agreed to contribute reviews & are thrilled to see them coming out cjasn.asnjournals.org/cc/kidney-geno…

(2/16)From methods & tools of discovery to clinical applications, there are #kidneyomics topics from all perspectives. Importantly @CJASN chose to make all reviews #OpenAccess. Given this, it seemed a great time to shine a light on the first 13 that have already been published.

(3/16) In the Intro, Caroline & I share our dual motivation for putting together this series. To inform the reader of the current clinical impact of genomics in nephrology & the tools & technologies that exist to empower future kidney genomic discovery cjasn.asnjournals.org/content/15/2/2…

(4/16)Drs. Martin Pollak & David Friedman @BID_NephFellows @BIDMChealth provide an overview on the genetic architecture of kidney disease & the role applied genomics in the nephrology clinic cjasn.asnjournals.org/content/15/2/2…

(5/16) Drs. Kathleen West, Erika Blacksher, @KCavanaugh_MD, Stephanie Fullerton, @EbeleUmeukeje, Bessie Young, & Wylie Burke share their perspectives on Returning Individual Genetic Results to Research Participants from a regulatory & ethical framework cjasn.asnjournals.org/content/early/…

(6/16) Drs. Ruth Dubin @UCSFNephrology & Eugene Rhee @MGHKidneys review Proteomics and Metabolomics in Kidney Disease cjasn.asnjournals.org/content/15/3/4…

(7/16)@GenxTIDVAL & Dr. Matthew Breyer @JanssenUS cover "The Use of Genomics To Drive Kidney Disease Drug
Discovery and Development" cjasn.asnjournals.org/content/early/…

(8/16) Drs. Mallory Downie, Sergio Lopez Garcia, Robert Kleta & Detlef Bockenhauer @ucl @GreatOrmondSt review Inherited Tubulopathies cjasn.asnjournals.org/content/early/…

(9/16) @HaojiaWu & @HumphreysLab @WUNephrology tackle the use of single cell sequencing, pluripotent stem cells, & kidney organoids for genomic discovery in kidney disorders cjasn.asnjournals.org/content/15/4/5…

(10/16)@AnnaLi_420, Dr. Jack Ingham, & @RLWczyk @nephrology_RMCH take on genetic disorders of the glomerular filtration barrier
cjasn.asnjournals.org/content/early/…

(11/16)Dr. Rik Westland, Kirsten Renkema, & @knoers @UMCU_Intl @researchumcg tackle "Clinical Integration of Genome Diagnostics for
Congenital Anomalies of the Kidney and Urinary Tract" cjasn.asnjournals.org/content/early/…

(12/16) Drs. Jennifer Schaub, Habib Hamidi, Lalita Subramanian & Matthias Kretzler @UMichKidney @MiKTMC review genomic discovery in nephrology from a Systems Biology approach cjasn.asnjournals.org/content/15/5/6…

(13/16) Drs. Adrienne Tin & Anna Köttgen @UMMCnews @UniFreiburg present "Genome-Wide Association Studies of CKD and
Related Traits"
cjasn.asnjournals.org/content/early/…

(14/16) @jenniejlin @KSusztak @NU_Nephrology @PennKidney review "Complexities of Understanding Function from
CKD-Associated DNA Variants" cjasn.asnjournals.org/content/early/…

(15/16)Dr. Elisa Molinari & @johnasayer @NIHRNewcBRC @newcastlehosps @uniofnewcastle cover the variety of disease models that can be used to more deeply understand the pathomechanisms of genetic kidney disorders cjasn.asnjournals.org/content/15/6/8…

(16/16)Finally, I suggest spending time w/all the bibliographies, which are themselves an invaluable resource. And thanks to @CJASN graphics professionals for their collaboration in making the images as great as the text. Stay tuned for the rest of the reviews soon. #kidneyomics